What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Sotyktu (Deucravacitinib)
Prescription Required
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Product Details
Description
Sotyktu is a prescribed medication containing deucravacitinib, which is indicated for treating moderate-to-severe plaque psoriasis in adults who are candidates for system therapy or phototherapy.
Sotyktu is a tyrosine kinase 2 (TYK2) inhibitor that targets key pathways involved in immune responses. It works by binding the regulatory domain of TYK2 and stabilizing the interaction between multiple domains on the target enzyme, causing an inhibition of activity. Ultimately, Sotyktu causes widespread inhibition of the immune response. The exact mechanism of psoriasis is unclear.
Directions
The usual dosage is 6 mg orally once daily, with or without food.
Take it exactly as your healthcare provider directs, following the prescribed dosage and schedule.
Ingredients
The active ingredient in Sotyktu is deucravacitinib.
Interactions
The most common drug-drug interactions with this drug include:
- Adalimumab
- Azathioprine
- Basiliximab
- Belatacept
- Certolizumab
- Chickenpox vaccine
- Ciclosporin
- Daclizumab
- Everolimus
- FluMist (Nasal spray flu vaccine)
- Golimumab
- Infliximab
- Leflunomide
- Measles, mumps, rubella (MMR) vaccine
- Methotrexate
- Mycophenolate mofetil
- Mycophenolic acid
- Nasal (nose) spray flu vaccine (FluMist)
- Rituximab
- Sirolimus
- Tacrolimus
- Tofacitinib
- Ustekinumab
- Yellow fever vaccine
Cautions
Inform your doctor about any existing medical conditions or allergies.
Adhere strictly to the prescribed treatment plan and promptly notify your healthcare provider of any unexpected reactions.
Follow your healthcare provider's guidance regarding the duration of treatment.
Sotyktu may increase the risk of infectious disease. Your doctor should test you for tuberculosis (TB) before starting this drug.
Use caution if you have a history of muscle wasting or rhabdomyolysis.
Your doctor should monitor liver function tests and cholesterol levels during treatment.
Sotyktu may increase the risk of lymphomas, a type of white blood cell cancer.
Side Effects
Common side effects of Sotyktu may include:
- Acne
- Blood creatine phosphokinase increased
- Folliculitis
- Herpes simplex
- Mouth ulcers
- Upper respiratory infections
References
Sotyku [package insert]. Princeton, NJ: Bristol-Myers Squibb; 2022.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14430
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