Description
SPIRIVA RESPIMAT (Tiotropium) is an inhaled medication prescribed to treat asthma or chronic obstructive pulmonary disease (COPD). Patients with these conditions may have trouble breathing because of bronchospasms, which is an abnormal tightening of the muscles of the lungs.
SPIRIVA RESPIMAT works by binding to receptors on the surface of muscle cells in the lung called muscarinic-receptors. When SPIRIVA RESPIMAT binds to these receptors, it causes lung muscles to relax, causing bronchodilation and making breathing easier.
Fact Table |
Formula |
C19H22BrNO4S2 |
License |
US FDA, US DailyMed |
Bioavailability |
19.5% |
Legal status |
Rx-Only |
Chemical Name |
Tiotropium |
Elimination half-life |
5–6 days |
Dosage (Strength) |
Respimat 2.5mcg (60 puffs/30 doses/inhaler), 18mcg (30 doses/Handihaler), 18mcg (30 doses/rotacaps) |
Pregnancy |
Not Harmful |
Brands |
Spiriva |
Protein binding |
72% |
PubChem CID |
5487426 |
MedlinePlus |
a604018 |
ChEBI |
90959 |
ATC code |
R03BB04 |
DrugBank |
DB01409 |
KEGG |
D01929 |
Routes of administration |
inhalation |
Directions
The SPIRIVA RESPIMAT dosage is different depending on what you are using the medication for.
- Asthma: Two inhalations of SPIRIVA RESPIMAT 1.25 mcg once daily
- COPD: Two inhalations of SPIRIVA RESPIMAT 2.5 mcg once daily
You must take the medication every day for the full effect. SPIRIVA RESPIMAT is not a rescue inhaler, and should not be used to treat acute bronchospasm.
Ingredients
The active ingredient in SPIRIVA is tiotropium bromide. Tiotropium is also the name for SPIRIVA RESPIMAT generic.
Cautions
Some patients have reported bronchospasm while taking SPIRIVA RESPIMAT and similar medication. If you have a worsening of symptoms, stop taking the medication and call your doctor.
Use SPIRIVA RESPIMAT with caution if you have narrow-angle glaucoma because this medication can make symptoms worse.
Anticholinergics like SPIRIVA RESPIMAT can worsen urinary retention. Use with caution if you have a history of prostatic hyperplasia or bladder neck obstruction.
Side Effects
The most common adverse reactions while taking SPIRIVA are:
- Dry mouth
- Dyspepsia
- Non-specific chest pain
- Pharyngitis
- Rhinitis
- Sinusitis
- Upper respiratory tract infection
- Urinary tract infection
The side effects may be different depending on whether you are treating asthma or COPD. Speak with your doctor or pharmacist for the entire list of side effects that applies to you.
References
- Spiriva Respimat [package insert]. Ridgefield, CT: Boehringer Ingelheim International; 2004.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 12309