May 17, 2025 by Barbara P. (CA, United States)
“I was a bit surprised by the supply chain: New Zealand to Mauritius to USA but all went smoothly.”
Supemtek (Quadrivalent Recombinant Influenze Vaccine)
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Prescription Required
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Product Details
Description
Supemtek® is a quadrivalent recombinant influenza vaccine developed by Sanofi Pasteur. It is designed to provide active immunization against influenza caused by two influenza A virus subtypes (H1N1 and H3N2) and two influenza B virus lineages (Victoria and Yamagata). Unlike traditional egg-based vaccines, Supemtek® is produced using recombinant DNA technology in an insect cell line, allowing for an exact genetic match to the World Health Organization (WHO) recommended strains . This method eliminates the risk of egg-adapted mutations, potentially enhancing vaccine effectiveness.
Fact Table
Formula
Recombinant HA proteins from 4 influenza strains
License
EMA (EU), 2020
Bioavailability
High (intramuscular absorption)
Legal status
Rx-only
Chemical Name
Quadrivalent recombinant influenza vaccine (QIVr)
Elimination half-life
Not applicable (vaccine antigen)
Dosage (Strength)
0.5 mL containing 45 µg of HA per strain (180 µg total)
Pregnancy
Use if clearly needed; consult physician
Brands
Supemtek
Protein binding
Not applicable
PubChem CID
Not assigned
MedlinePlus
a621048
ChEBI
Not listed
ATC code
J07BX03
DrugBank
DB11621
KEGG
D10962
Routes of administration
Intramuscular injection
Directions
Supemtek® is administered as a single 0.5 mL intramuscular injection, preferably into the deltoid muscle of the upper arm. It is indicated for adults 18 years of age and older. Annual vaccination is recommended, as influenza virus strains and immunity levels can change each year .
Ingredients
Each 0.5 mL dose of Supemtek® contains:
- 45 micrograms of recombinant hemagglutinin (HA) protein per strain, totaling 180 micrograms for all four strains
- Polysorbate 20 (E432)
- Sodium chloride
- Sodium phosphate monobasic monohydrate
- Sodium phosphate dibasic dodecahydrate
- Water for injections
Supemtek® is egg-free, latex-free, and contains no preservatives or antibiotics .
Contraindications
Supemtek® is contraindicated in individuals with:
- Hypersensitivity to the active substances or any of the excipients listed above
- Known allergy to octylphenol ethoxylate, a trace residual from the manufacturing process
Cautions
- Postpone vaccination in individuals with acute febrile illness until recovery
- Immunocompromised individuals may have a diminished immune response
- As with all vaccines, appropriate medical treatment should be available in case of an anaphylactic reaction
- Supemtek® may not provide protection against all circulating influenza strains or in all vaccinated individuals
Side Effects
Very common (may affect more than 1 in 10 people):
- Injection site pain and tenderness
- Fatigue
- Headache
- Muscle and joint pain (in adults 18–49 years of age)
Common (may affect up to 1 in 10 people):
- Nausea
- Redness, swelling, or hardness at the injection site
- Fever (>38°C) (in adults 18–49 years of age)
- Shivering
- Muscle and joint pain (in adults 50 years of age and older)
Uncommon (may affect up to 1 in 100 people):
- Dizziness
- Gastrointestinal symptoms (e.g., diarrhea, vomiting)
- Lymphadenopathy (swollen lymph nodes)
Popular Questions
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IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14596
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Product Reviews
We're currently collecting product reviews for this item. In the meantime, here are some reviews from our past customers sharing their overall shopping experience.4.8Out of 5.0
Overall Rating95%of customers that buy
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them a 4 or 5-Star rating.May 17, 2025 by Robert A. (Washington, United States)“Easy”May 17, 2025 by Linda C. (New Hampshire, United States)“Great prices!!”May 15, 2025 by Carole D. (Illinois, United States)“So easy to place my order.”May 15, 2025 by Carol B. (New Jersey, United States)“Great service. Exemplary prices. I went on chat before ordering and they confirmed my refill.”May 15, 2025 by M J. (California, United States)“Thanks for sooner than expected.”May 15, 2025 by Shelley E. (Florida, United States)“This company is exceptional and I will always get my medications from them. They have exceptional customer service along with great products.”May 15, 2025 by Edie L. (California, United States)“Cust svc. always excellent.”May 15, 2025 by Michael G. (Rhode Island, United States)“Good service and price.”May 15, 2025 by Carle N. (Missouri, United States)“Have created an account, put in an order, waiting for physician to fax you an order”
