A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Tecfidera is a prescription medication used to treat multiple sclerosis (MS). MS is a serious and progressive disease where the immune system attacks the protective layer of the nerve cells. Symptoms are varied and affect every part of the body.
Tecfidera is approved to treat the following relapsing forms of MS:
Tecfidera works by activating a cellular pathway called Nrf2, which is involved in the cellular response to oxidative stress. By activating this pathway, Tecfidera helps to treat MS. Tecfidera has been shown to reduce the number of relapses, delay the progression of disability, and slow the development of brain lesions.
Tecfidera should only be prescribed by a physician that specializes in the treatment of MS.
The starting dose of Tecfidera is 120 mg by mouth twice daily for seven days. After seven days, the dose is increased to 240 mg by mouth twice daily.
This medication comes as a delayed-release capsule and should not be crushed or chewed. Swallow the capsule whole with or without food.
The active ingredient in Tecfidera is Dimethyl Fumarate, which is the name of the Tecfidera generic.
Tecfidera can interact with the following:
This medication should be stopped if an allergic reaction or serious swelling occurs.
Tecfidera may cause a condition known as progressive multifocal leukoencephalopathy (PML) and should be stopped at the first sign suggesting this condition.
Your doctor should monitor liver function and blood cell function before and during treatment.
Common adverse reactions to Tecfidera may include:
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Tecfidera [package insert]. Cambridge, MA: Biogen; 2021.