Description
Teosyal is a line of injectable dermal fillers made from non-animal stabilized hyaluronic acid (HA), developed by Teoxane Laboratories. It is designed for aesthetic facial treatments including wrinkle reduction, facial contouring, lip enhancement, and skin hydration. Teosyal products are formulated to integrate seamlessly with the skin's tissue, offering natural-looking and long-lasting results. The range includes several formulations with varying viscosities and cross-linking levels to suit different indications and injection depths, such as Teosyal RHA (Resilient Hyaluronic Acid) for dynamic facial areas and Teosyal PureSense for enhanced patient comfort.
Fact Table |
Formula | (C14H21NO11)n (cross-linked hyaluronic acid) |
License | CE marked (EU); FDA-cleared (U.S., select products) |
Bioavailability | Local (intradermal injection) |
Legal status | Medical device (Rx in most countries) |
Chemical Name | Cross-linked sodium hyaluronate |
Elimination half-life | Varies (typically 6–18 months depending on product and location) |
Dosage (Strength) | Vials or syringes: 1 mL prefilled (varies by product line) |
Pregnancy | Contraindicated (not tested in pregnancy) |
Brands | Teosyal® RHA, Teosyal® Kiss, Teosyal® Ultra Deep, Teosyal® Redensity I & II |
Protein binding | Not applicable |
PubChem CID | 24759 (hyaluronic acid) |
MedlinePlus | Not listed (cosmetic device) |
ChEBI | CHEBI:16336 (hyaluronic acid) |
ATC code | None (medical device) |
DrugBank | DB08818 (hyaluronic acid) |
KEGG | Not applicable |
Routes of administration | Intradermal injection |
Directions
Teosyal should be administered by a licensed healthcare professional trained in dermal filler techniques. The product is injected intradermally or subcutaneously, depending on the indication and formulation. The treatment area should be cleaned and disinfected prior to injection. For patient comfort, many Teosyal formulations include lidocaine. After injection, gentle massage may be applied to ensure even distribution. Results are typically visible immediately, with optimal outcomes assessed after any initial swelling subsides.
Ingredients
The core ingredient in all Teosyal products is:
- Cross-linked hyaluronic acid (concentration varies by product, typically between 15 mg/mL and 25 mg/mL)
- Some formulations also contain lidocaine hydrochloride (0.3%) as a local anesthetic
Other excipients may include phosphate-buffered saline for pH stability and tissue compatibility.
Contraindications
Teosyal is contraindicated in patients who:
- Have a known hypersensitivity to hyaluronic acid, lidocaine, or amide-type local anesthetics
- Have active skin infections or inflammation at the injection site
- Are prone to hypertrophic scarring or keloid formation
- Are pregnant or breastfeeding
- Have autoimmune disorders or undergoing immunotherapy (unless deemed appropriate by a specialist)
Cautions
Teosyal should be used with caution in patients with bleeding disorders or those taking anticoagulant therapy. Avoid injection into or near blood vessels to prevent vascular complications. Patients should avoid exposure to extreme temperatures, saunas, and vigorous facial manipulation for at least one week after treatment. Temporary post-treatment swelling, redness, or bruising may occur. A full medical history should be obtained prior to treatment to assess risk factors.
Side Effects
Side effects are generally mild and transient, and may include:
- Redness, swelling, or tenderness at the injection site
- Bruising or hematoma formation
- Itching or mild discomfort
- Very rarely, allergic reactions or vascular occlusion
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 9841