What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Tivorbex (Indomethacin)


Tivorbex (Indomethacin)

Prescription Required


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  • Product Details


    Tivorbex is an NSAID that your healthcare provider may prescribe for the treatment of short-term pain. It works by reducing pain and inflammation.

    Fact Table




    US FDA


    ~100% (oral), 80–90% (rectal)

    Legal status


    Chemical Name


    Elimination half-life

    2.6-11.2 hours (adults), 12-28 hours (infants)

    Dosage (Strength)



    Consult Doctor


    Indocid, Indocin, Tivorbex

    Protein binding


    PubChem CID






    ATC code






    Routes of administration

    By mouth


    Take Tivorbex at the lowest dosage and for the shortest period to reduce the risk of serious side effects.

    The dosage ranges from 20-40 mg by mouth two to three times daily with food.


    The active ingredient in Tivorbex is indomethacin.


    Tell your pharmacist and doctor if you are taking any of the following drugs:

    • Abrocitinib
    • Acemetacin
    • Aminolevulinic Acid 
    • Apixaban
    • Bemiparin
    • Cyclosporine
    • Dabigatran Etexilate
    • Diflunisal
    • Edoxaban
    • Enoxaparin
    • Heparin
    • Ketorolac
    • Lithium
    • Loop Diuretics
    • Macimorelin
    • Methotrexate
    • Mifamurtide
    • Nonsteroidal Anti-Inflammatory Agents
    • Phenylbutazone
    • Pralatrexate
    • Rivaroxaban
    • Salicylates
    • Selective Serotonin Reuptake Inhibitors
    • Sincalide
    • Sodium Phosphates
    • Tenofovir Products
    • Tenoxicam
    • Tiludronate
    • Triamterene
    • Urokinase
    • Vitamin K Antagonists


    Tell your doctor if you have a history of cardiovascular disease, gastrointestinal bleeding, liver problems, high blood pressure, edema, or psychiatric illness before starting Tivorbex.

    Ask your doctor and pharmacist for a full list of warnings before starting Tivorbex.

    Side Effects

    Common adverse reactions to Tivorbex may include:

    • Abdominal distress
    • Abdominal pain
    • Acute respiratory distress
    • Alopecia
    • Anaphylaxis
    • Anemia
    • Angioedema
    • Anorexia
    • Anxiety
    • Asthma
    • Auditory disturbance
    • Bloating
    • Blurred vision
    • Breast tenderness
    • Cardiac arrhythmia
    • Cardiac failure
    • Vasculitis
    • Chest pain
    • Confusion
    • Constipation
    • Decreased appetite
    • Depression
    • Diaphoresis
    • Diarrhea
    • Dizziness
    • Drowsiness
    • Dyspepsia
    • Dyspnea
    • Ecchymoses
    • Edema
    • Epigastric pain
    • Erythema multiforme
    • Erythema nodosum
    • Exfoliative dermatitis
    • Fatigue
    • Fever
    • Flatulence
    • Fluid retention
    • Flushing
    • Gastroenteritis
    • Gastrointestinal hemorrhage
    • Gastrointestinal perforation
    • Gastrointestinal ulcer
    • Headache
    • Heartburn
    • Hepatic failure
    • Hot flash
    • Hyperglycemia
    • Hyperhidrosis
    • Hyperkalemia
    • Hypertension
    • Hypotension
    • Ileitis
    • Immune thrombocytopenia
    • Insomnia
    • Intestinal obstruction
    • Intestinal stenosis
    • Jaundice
    • Leukopenia
    • Maculopathy
    • Malaise
    • Nausea
    • Nervousness
    • Palpitations
    • Pancreatitis 
    • Paresthesia
    • Peptic ulcer
    • Peripheral neuropathy
    • Postoperative hemorrhage
    • Presyncope
    • Pruritus
    • Psychosis
    • Pulmonary edema
    • Rectal hemorrhage
    • Renal insufficiency
    • Seizure
    • Shock
    • Skin Rash
    • Stevens-Johnson syndrome
    • Swelling
    • Syncope
    • Tachycardia
    • Tinnitus
    • Toxic epidermal necrolysis
    • Urticaria
    • Vaginal hemorrhage
    • Vertigo
    • Vomiting
    • Weight gain


    Tivorbex. Philadelphia, PA: Iroko Pharmaceuticals, LLC; 2014.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13629

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