What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Tobrex (TobramycIin)
Prescription Required
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Product Details
Description
Tobrex is a prescription eye medication for the treatment of certain types of eye infections. Eye infections can be viral, bacterial, or fungal. Tobrex is an antibacterial that treats infections from bacteria.
Tobrex works by blocking the creation of bacterial proteins. Proteins are necessary for life, and blocking their synthesis kills the infective bacteria.
Fact Table
Formula
C18H37N5O9
License
EU EMA, US FDA
Bioavailability
11.7%
Legal status
Rx Only
Chemical Name
Tobramycin
Elimination half-life
2–3 hrs
Dosage (Strength)
0.3%
Pregnancy
Consult Doctor
Brands
Nebcin, Tobrex, Tobi
Protein binding
Not bound
PubChem CID
36294
MedlinePlus
a682660
ChEBI
28864
ATC code
J01GB01
DrugBank
DB00684
KEGG
D00063
Routes of administration
IV, IM, inhalation, eye drops/ointment
Directions
Take Tobrex for as long as directed by your doctor. Using it for less than the prescribed amount of time may cause the development of bacterial resistance. However, using it for longer than prescribed may also cause this problem.
The usual dosage is 1-2 drops every four eyes into the affected eyes for mild or moderate infections. For severe infections, the directions are to use every two hours.
Do not touch the tip of the dropper to the eye as this may cause contamination of the Tobrex bottle.
Ingredients
Tobramycin is the active ingredient in Tobrex.
Store this drug at room temperature and discard it as soon as it reaches the expiration date on the bottle.
Interactions
There are no known significant interactions. However, Tobrex should not be used simultaneously as other eye medications.
Cautions
Do not wear contact lenses while you are using this product.
Do not use this drug if you are allergic to aminoglycoside medications.
Side Effects
Some of the more common tobramycin side effects may include:
- Anaphylaxis
- Conjunctival erythema
- Erythema multiforme
- Eyelid edema
- Eyelid pruritus
- Hypersensitivity reaction
- Ocular toxicity
- Skin rash
- Stevens-Johnson syndrome
Tell your doctor and pharmacist if you experience any of the above while taking this drug.References
Tobrex [package insert]. Fort Worth, TX: Alcon Laboratories, Inc.; 2012.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 5261
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