Toujeo (Insulin Glargine)

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  • Product Details


    TOUJEO (insulin glargine) is prescribed to treat high blood sugar (hyperglycemia) in people with diabetes mellitus.

    TOUJEO insulin is a long-acting insulin that is administered once daily, and its effects work for about 24 hours in most people. 

    Compared to other long-acting insulin products, TOUJEO has a higher concentration of 300 units per milliliter. The higher concentration means that people who inject large amounts of insulin can inject the same amount of medication in a lower volume.

    TOUJEO SOLOSTAR pens can hold up to 450 units of insulin (1.5 milliliters.)


    Administer TOUJEO subcutaneously once-daily at the same time each day. Do not change the injection time without speaking to your doctor first.

    Rotate injections sites between the abdomen, thighs, and back of the arm to help avoid lipodystrophy.

    Monitor blood sugar closely when making any changes to an insulin regimen.


    The active ingredient in TOUJEO is insulin glargine.


    The following medications can change blood sugar, requiring that the dose of TOUJEO be adjusted:

    • Alcohol
    • Atypical Antipsychotics
    • Beta-blockers
    • Clonidine
    • Corticosteroids
    • Disopyramide
    • Diuretics
    • Estrogens/Progesterones
    • Fibrates
    • Fluoxetine
    • Isoniazid
    • Lithium
    • Monoamine Oxidase Inhibitors (MAOIs)
    • Niacin
    • Oral antidiabetic agents
    • Pentoxifylline
    • Phenothiazine derivatives
    • Pramlintide
    • Propoxyphene
    • Protease inhibitors
    • Salicylates
    • Somatostatin Analogues
    • Somatropin
    • Sulfonamide Antibiotics
    • Sympathomimetic agents
    • Thyroid replacement medication

    Tell your doctor if you are taking any of the above.


    Hypoglycemia is a common side effect of TOUJEO and other insulin products. The symptoms of hypoglycemia can include:

    • Anxiety
    • Confusion
    • Dizziness
    • Fatigue
    • Hunger
    • Irritability
    • Pale skin
    • Sweating
    • Tremor

    Read the label on the TOUJEO pen carefully before each injection. This helps to prevent medication errors.

    While taking insulin, your doctor should monitor potassium levels, kidney function, and liver function.

    Tell your doctor if you have a history of cardiovascular disease.

    Side Effects

    • Allergic reactions
    • Edema
    • Hypoglycemia
    • Injection site reactions
    • Lipodystrophy
    • Pruritis
    • Rash
    • Weight gain


    TOUJEO [package insert] Bridgewater, NJ: Sanofi-Aventis; 2015.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13367

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