Description
Tradjenta is classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used with diet and exercise to lower blood sugar levels in adults with type 2 diabetes.
The generic name for Tradjenta is Linagliptin.
Fact Table |
Formula |
C25H26N8O2 |
License |
US FDA, EU EMA, US DailyMed |
Bioavailability |
~30% |
Legal status |
Rx-Only |
Chemical Name |
Linagliptin |
Elimination half-life |
~24 hours |
Dosage (Strength) |
5mg |
Pregnancy |
Not recommended |
Brands |
Tradjenta |
Protein binding |
75–99% |
PubChem CID |
10096344 |
MedlinePlus |
a611036 |
ChEBI |
68610 |
ATC code |
A10BH05 |
DrugBank |
DB08882 |
KEGG |
D09566 |
Routes of administration |
By mouth |
Directions
Tradjenta is available as a 5 mg oral tablet. The dose of Tradjenta is 5 mg by mouth once daily with or without food.
Ingredients
The active ingredient in Tradjenta is Linagliptin, a DPP-4 inhibitor.
Contraindications
Talk to your doctor about your allergies. Do not take Tradjenta if you are allergic to linagliptin or any of the other ingredients contained in Tradjenta. Reactions such as anaphylaxis, angioedema, bronchial hyperreactivity, exfoliative skin, or urticaria have been reported.
Warnings and Precautions
- Tradjenta may interact with some medications. Before you start Tradjenta, be sure to tell your doctor about any prescription and over-the-counter medications, vitamins, and supplements you take.
- Tradjenta may cause pancreatitis. You should seek medical attention if you experience stomach pain that won't go away.
- Heart failure has been reported with other DPP-4 inhibitors. The benefits and risks should be considered if you are at risk for heart failure.
- Tradjenta can cause low blood sugar levels, especially if taken with other medications that can lower blood sugar. Monitor symptoms of low blood sugar such as sweating, nervousness, shakiness, hunger, confusion, irritability, and/or rapid heart beat. Be sure to treat low blood sugar as your doctor has instructed.
- Some people have reported joint pain while taking DPP-4 inhibitors like Tradjenta. Tell your doctor if you develop joint pain.
- A skin reaction called bullous pemphigoid may occur in patients who take DPP-4 inhibitors such as Tradjenta. Contact your doctor immediately if you develop blisters.
- Tell your doctor if you are pregnant or plan to become pregnant.
- Tell your doctor if you are breastfeeding or plan to breastfeed.
Side Effects
Tell your doctor if you experience severe side effects or side effects that are bothersome or won't go away. The most common side effects of Tradjenta (linagliptin) are:
- Cough
- Diarrhea
- Stuffy or runny nose
- Sore throat
References:
- TRADJENTA Prescribing Information. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2020.
- Tradjenta (linagliptin). Accessed November 18, 2021. https://www.tradjenta.com.
About Dr. Savannah Muncy (Page Author)
Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 12498