What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Tribenzor (Amlodipine / Olmesartan / HCT)
Also Known as Sevikar HCT
Prescription Required
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Product Details
Description
Tribenzor is made of three medications:
- Olmesartan medoxomil - angiotensin II receptor blocker (ARB)
- Amlodipine - dihydropyridine calcium channel blocker (CCB)
- Hydrochlorothiazide - thiazide diuretic
Tribenzor is used to treat high blood pressure.
Fact Table
Formula
C56H63Cl2N11O15S2
License
US DailyMed
Bioavailability
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Legal status
Rx-Only
Chemical Name
Amlodipine / Olmesartan / HCT
Elimination half-life
5.6 and 14.8 hours
Dosage (Strength)
5-20-12.5mg, 5-40-12.5mg, 5-40-25mg, 10-40-12.5mg, 10-40-25mg
Pregnancy
Consult Doctor
Brands
Tribenzor
Protein binding
99%
PubChem CID
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MedlinePlus
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ChEBI
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ATC code
C09DX03
DrugBank
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KEGG
D10288
Routes of administration
By Mouth
Directions
Tribenzor dosage form: tablets
Tribenzor (olmesartan medoxomil/amlodipine/hydrochlorothiazide) strengths:
20 mg/5 mg/12.5 mg, 40 mg/5 mg/12.5 mg, 40 mg/5 mg/25 mg, 40 mg/10 mg/12.5 mg, 40 mg/10 mg/25 mg
Once you are prescribed and buy Tribenzor, Tribenzor is taken by mouth once daily.
Ingredients
The active ingredients in Tribenzor are Olmesartan medoxomil, Amlodipine, and Hydrochlorothiazide.
Contraindications
Do not take Tribenzor if you have abnormally less urine or if you are unable to urinate.
Do not take Tribenzor if you are allergic to any of the ingredients contained in Tribenzor.
Do not take Tribenzor if you are allergic to sulfonamide-derived drugs.
Do not take Tribenzor if you have not taken any other medications for your blood pressure before.
Cautions
WARNING: FETAL TOXICITY
See full prescribing information for complete boxed warnings.
When pregnancy is detected, discontinue Tribenzor as soon as possible.
Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus.
- Before you start taking Tribenzor, tell your doctor if you are pregnant, suspect that you are pregnant, or plan to become pregnant. Tribenzor may cause fetal toxicity that can result in injury or death to the fetus.
- Before you start taking Tribenzor, tell your doctor if you are breastfeeding or plan to start breastfeeding. Breastfeeding is not recommended while taking Tribenzor.
- Before you start taking Tribenzor, tell your doctor if you have:
- Kidney problems
- Liver problems
- Heart problems
- Diabetes
- Glaucoma
- Lupus
- Gout
- Diarrhea or vomiting
- Allergies
- Bronchial asthma
- Before you start taking Tribenzor, be sure to let your doctor know about any prescription and over-the-counter medications you take, including vitamins and supplements.
- Tribenzor can cause low blood pressure, which can make you feel dizzy or faint. You should avoid drinking alcohol with Tribenzor. Your blood pressure may drop too low if you drink alcohol. Monitor your blood pressure while taking Tribenzor.
Side Effects
Side effects may occur with Tribenzor. Tribenzor side effects including:
- Low blood pressure
- Dizziness
- Swelling of the hands or legs
- Swelling of the joints
- Fatigue
- Muscle spasms
- Nausea
- Nasopharyngitis
- Upper respiratory infections
- Urinary tract infection
- Diarrhea
References:
TRIBENZOR Prescribing Information. Basking Ridge, NJ: Daiichi Sankyo, Inc.; 2020.
Tribenzor (olmesartan medoxomil, amlodipine, hydrochlorothiazide). Accessed November 18, 2021.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13034
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