What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Triluron (Sodium Hyaluronate)


Triluron (Sodium Hyaluronate)

Prescription Required

20mg / 2ml

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  • Product Details


    Triluron (sodium hyaluronate) is an injection used to treat knee pain caused by osteoarthritis in patients who did not respond well to conservative treatment or to simple pain relievers.

    Fact Table




    US FDA



    Legal status


    Chemical Name

    Sodium Hyaluronate

    Elimination half-life

    3 to 5 min

    Dosage (Strength)

    2ml Syringe





    Protein binding


    PubChem CID






    ATC code






    Routes of administration



    Triluron is available in 2 mL glass vials and 2 mL pre-filled syringes to be injected into the intra-articular space of the knee. Use immediately once the syringe packaging or the vial's seal has been opened. Each vial or syringe is for single use only and any remaining Triuloron should be discarded. 

    If you have any questions, ask your doctor or pharmacist.


    Each 2 mL glass vial or 2 mL pre-filled syringe contains 20 mg of sodium hyaluronate.


    Do not use Triluron if you are allergic to hyaluronate or any other ingredient in Triluron.

    Do not use Triluron if you have had or currently have a skin disease or infection at or near the injection site.


    • Before you start using Triluron, inform your doctor:
      • Of any allergies you have
      • Of any medications you take, including prescription and over-the-counter medications.
      • Of any health conditions you have
      • If you are pregnant or plan to become pregnant
      • If you are nursing or plan to nurse your baby
    • Triluron should be administered using strict aseptic technique to prevent injection site infections.
    • Do not use Triluron with disinfectants that contain quaternary ammonium salts for the skin. Precipitation of hyaluronate can occur.
    • Joint pain and/or swelling may occur after injecting Triluron. 
    • Inflammation in the knee may occur after injecting Triluron if you have rheumatoid arthritis or gouty arthritis. 
    • Do not overexert yourself within at least 48 hours of using Triluron.
    • Store Triluron away from light and in temperatures below 77°F (25° C). Do not store it in the freezer.

    Side Effects

    The most common side effects of Triluron injections include stomach problems, pain at the injection site, knee swelling, headache, itchy skin, and rash.

    Call your doctor right away if you experience any side effects that worsen or won't go away.


    1. Triluron Prescribing Information. Florham Park, NJ: Fidia Pharma USA Inc.; 2019.
    2. Triluron Patient Information. Florham Park, NJ: Fidia Pharma USA Inc.; 2019.

    Frequently Asked Questions about Triluron (Sodium Hyaluronate)

    What is Triluron?

    Triluron is a sterile injection containing sodium hyaluronate, a natural substance found in your joints that acts as a lubricant and shock absorber.

    What is it used for?

    Triluron is used to relieve knee pain caused by osteoarthritis, especially if other treatments like painkillers or physical therapy haven't helped enough.

    How does it work?

    In osteoarthritis, the natural hyaluronate in your joints can be depleted or break down. Triluron replaces this lost hyaluronate, cushioning your joint and potentially reducing pain.

    How is it administered?

    Triluron is injected directly into your knee joint by a healthcare professional, usually as a series of 3 weekly injections.

    How long does it take to work?

    You may start feeling pain relief within a few days, but it can take up to several weeks for the full effect.

    What are the side effects?

    Common side effects include injection site pain, swelling, redness, and warmth. More serious side effects like infection are rare.

    Who shouldn't use Triluron?

    Triluron is not suitable if you're allergic to hyaluronate, have an active joint infection, or certain skin conditions near the injection site.

    Can I take other medications with Triluron?

    Tell your doctor about all medications you're taking, including supplements, to avoid potential interactions.

    Are there alternative treatments for knee osteoarthritis?

    Yes, options like weight management, exercise, physical therapy, pain medication, and other joint injections exist. Discuss all options with your doctor.

    Where can I learn more about Triluron?

    Talk to your doctor or healthcare professional, or visit the official Triluron website for more detailed information.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13590

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