What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Tukysa (Tucatinib)
Prescription Required
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Product Details
Description
Tukysa is a medication available by prescription that is used with:
- Trastuzumab and capecitabine to treat breast cancers that have spread to other parts of the body, including the brain, in adults who have received one or more prior regimens
- Trastuzumab to treat adults with colorectal cancer that has spread to other parts of the body despite treatment with chemotherapy
Tukysa comes in 50 mg and 150 mg tablets for oral use.
Directions
Take Tukysa exactly as your doctor has prescribed. Tell your doctor or pharmacist about any questions or concerns you have about the medication.
The recommended dose is 300 mg by mouth twice a day. The medication may be taken with or without food.
Patients with liver problems may require a lower dose.
Ingredients
Tucatinib is the active ingredient contained in each Tukysa tablet.
The core of each tablet contains copovidone, crospovidone, sodium chloride, potassium chloride, sodium bicarbonate, colloidal silicon dioxide, magnesium stearate, and microcrystalline cellulose. The coating of each tablet contains polyvinyl alcohol, titanium dioxide, macrogol/polyethylene glycol, talc, and yellow iron oxide non-irradiated.
Contraindications
There are no contraindications per Tukysa’s most recent Prescribing Information.
Cautions
- Before you begin treatment with Tukysa, the following should be discussed with your doctor:
- All the prescription and nonprescription medications you take
- Your allergies
- Your past medical history and current health problems
- Your pregnancy or breastfeeding status
- Tukysa can cause severe diarrhea that may lead to dehydration, acute kidney damage, and death.
- Tukysa can cause liver damage.
- Tukysa can cause harm to an unborn baby. Effective methods of birth control should be used.
Side Effects
Diarrhea, hand-foot syndrome, nausea, liver damage, vomiting, inflamed/sore mouth, decreased appetite, anemia, rash, fatigue, stomach pain, infusion-related reactions, and fever are common Tukysa side effects. However, other side effects can occur. Call your doctor immediately if you experience bothersome or persistent side effects.
Reference:
Tukysa. Bothell, WA: Seagen Inc.; 2023.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13756
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