What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Tykerb (Lapatinib Ditosylate)


Tykerb (Lapatinib Ditosylate)

Prescription Required


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  • Product Details


    Tykerb is a prescription drug that your doctor may prescribe for the treatment of metastatic breast cancer. Tykerb is not a chemotherapy medication but may be used in addition to a chemotherapy regimen.

    Tykerb is typically prescribed by healthcare providers that specialize in the treatment of cancer. When you take this drug, extra monitoring may be required.

    Tykerb works by blocking a protein called endothelial growth factor receptor (EGFR). EGFR has several roles in the body, and in certain types of cancer, it can cause the replication of cancerous cells. Blocking EGFR helps to control the spread of cancer.


    Take this drug exactly as prescribed by your healthcare team.


    The active ingredient in this drug is lapatinib ditosylate.


    Common drug-drug interactions with this medication may include:

    • Afatinib
    • Alpelisib
    • Berotralstat
    • Bilastine
    • Cladribine
    • Colchicine
    • CYP3A4 Inducers
    • Dexamethasone
    • Digoxin
    • Doxorubicin
    • Fexinidazole
    • Fusidic Acid
    • Grapefruit Juice
    • Lefamulin
    • Lemborexant
    • Lomitapide
    • Lonafarnib
    • Pazopanib
    • Pimozide
    • Relugolix
    • Relugolix, Estradiol, and Norethindrone
    • Rimegepant
    • Sirolimus
    • Sirolimus
    • St John's Wort
    • Topotecan
    • Ubrogepant
    • Venetoclax
    • Vincristine


    Tell your doctor if you have a history of liver problems before starting this drug.

    Use caution if you have a history of heart problems before taking this drug.

    Side Effects

     Common adverse reactions include:

    • Alopecia
    • Anaphylaxis
    • Anorexia
    • Asthenia
    • Back pain
    • Decreased hemoglobin
    • Decreased left ventricular ejection fraction
    • Decreased neutrophils
    • Decreased platelet count
    • Diarrhea
    • Dyspepsia 
    • Dyspnea
    • Epistaxis
    • Fatigue
    • Hepatotoxicity
    • Hypersensitivity reaction
    • Increased serum alanine aminotransferase
    • Increased serum aspartate aminotransferase
    • Increased serum bilirubin
    • Insomnia
    • Interstitial pulmonary disease
    • Limb pain
    • Nail disease
    • Nausea
    • Palmar-plantar erythrodysesthesia 
    • Paronychia
    • Pneumonitis
    • Prolonged QT interval
    • Pruritus
    • Skin fissure
    • Skin rash
    • Stevens-Johnson syndrome
    • Stomatitis
    • Toxic epidermal necrolysis
    • Ventricular arrhythmia
    • Vomiting
    • Xeroderma 


    Tykerb [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2007.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 11405

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