What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ubrelvy (Ubrogepant)
Prescription Required
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Product Details
Description
Your doctor may prescribe Ubrelvy (Ubrogepant) to treat acute migraine headaches in adults. Migraine headaches are characterized by intense, throbbing pain on one side of the head, often accompanied by sensitivity to light and sound, nausea, and vomiting.
Ubrelvy belongs to a class of drugs called CGRP receptor antagonists, which work by blocking the action of calcitonin gene-related peptide (CGRP), a molecule involved in headaches associated with migraines.
Fact Table
Formula
C29H26F3N5O3
License
US DailyMed
Bioavailability
40% Oral
Legal status
Rx-Only
Chemical Name
Ubrogepant
Elimination half-life
5 to 7 hours
Dosage (Strength)
100mg
Pregnancy
Consult Doctor
Brands
Ubrelvy
Protein binding
87%
PubChem CID
68748835
MedlinePlus
a620016
ChEBI
Not Available
ATC code
L01FA02
DrugBank
N02CD04
KEGG
D10673
Routes of administration
Oral
Directions
Ubrelvy comes in tablet form and is taken orally with or without food.
The usual dose is one tablet (50mg or 100mg) taken as soon as possible after the onset of a migraine headache.
If needed, patients may take a second dose at least 2 hours after the first dose, but no more than 2 doses should be taken within 24 hours. The most someone should take in 24 hours is 200 mg.
Ingredients
The active ingredient in Ubrelvy is ubrogepant.
Interactions
Common drug-drug interactions occur between Ubrelvy and:
- BCRP/ABCG2 Inhibitors
- Ciprofloxacin
- Clofazimine
- CycloSPORINE
- CYP3A4 Inducers
- CYP3A4 Inhibitors
- Deferasirox
- Erdafitinib
- Fexinidazole
- FluvoxaMINE
- Fusidic Acid
- Futibatinib
- Gilteritinib
- Interleukin-6 (IL-6) Inhibiting Therapies
- Ivosidenib
- Lasmiditan
- Mavacamten
- Olutasidenib
- Pacritinib
- P-glycoprotein/ABCB1 Inhibitors
- Pitolisant
- Pretomanid
- Spironolactone
- St John's Wort
- Taurursodiol
- Treosulfan
- Voxilaprevir
Cautions
Ubrelvy should not be taken by people with severe liver problems or a history of allergic reactions to ubrogepant. Mild to moderate liver problems may require a dosage adjustment.
It is important to inform your doctor if you have liver or kidney problems, as the dose of Ubrelvy may need to be adjusted.
Ubrelvy should not be taken during pregnancy or while breastfeeding.
Side Effects
Common adverse reactions may include
- Drowsiness
- Nausea
- Xerostomia
Tell your doctor or pharmacist if you experience any side effects while taking this drug.
References
- Ubrelvy [package insert]. Madison, NJ: Allergan USA, Inc; 2019.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13856
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