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Uzedy (Risperidone)

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  • Product Details

    Description

    Uzedy (risperidone) is an atypical antipsychotic medication used to treat schizophrenia and bipolar I disorder (maintenance) in adults. This monthly injection releases the medication over time and is thought to relieve symptoms by blocking certain brain receptors, especially dopamine (D2) and serotonin (5-HT2) receptors. However, its exact mechanism of action isn’t fully understood. You can buy Uzedy injection from Canada Pharmacy with a valid prescription from your healthcare provider.

    Fact Table

    Formula

    C23H27FN4O2

    License

    US FDA, TGA; Health Canada as Longavo

    Bioavailability

    Not determined for Uzedy; oral risperidone approximately 70%

    Legal status

    Rx-only; Schedule 4 (AU); Prescription (CA)

    Chemical Name

    3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one

    Elimination half-life

    Mean apparent half-life approximately 14 to 22 days

    Dosage (Strength)

    Once monthly: 50 mg, 75 mg, 100 mg, 125 mg; once every 2 months: 100 mg, 150 mg, 200 mg, 250 mg; subcutaneous injection

    Pregnancy

    May cause neonatal extrapyramidal and/or withdrawal symptoms with third-trimester exposure; consult a doctor

    Brands

    Uzedy, Longavo, Risperdal, Risperdal Consta, Perseris, Okedi

    Protein binding

    Risperidone: approximately 90%; 9-hydroxyrisperidone: 77%

    PubChem CID

    5073

    MedlinePlus

    a694015

    ChEBI

    8871

    ATC code

    N05AX08

    DrugBank

    DB00734

    KEGG

    D00426

    Routes of administration

    Subcutaneous

    Directions

    Uzedy isn’t an at-home treatment and must be administered by a healthcare professional. After ensuring you tolerate the medication by prescribing oral risperidone, your doctor will inject Uzedy under the skin in your abdomen or upper arm. Uzedy dosing depends on the condition being treated and may be adjusted if you have kidney or liver problems.

    Schizophrenia:

    Patients typically receive the first Uzedy injection the day after their last oral dose:

    • Oral 2 mg (daily) ? Uzedy 50 mg (monthly) or 100 mg (every two months)
    • Oral 3 mg (daily) ? Uzedy 75 mg (monthly) or 150 mg (every two months)
    • Oral 4 mg (daily) ? Uzedy 100 mg (monthly) or 200 mg (every two months)
    • Oral 5 mg (daily) ? Uzedy 125 mg (monthly) or 250 mg (every two months)

    If your Uzedy dosing schedule changes from monthly to every 2 months, the first dose under the new schedule is given at the next scheduled injection date.

    Bipolar I Disorder Maintenance:

    After your doctor has ensured that your body tolerates oral risperidone, Uzedy is given once monthly, either alone or with lithium or valproate.

    • Oral 2 mg (daily) ? Uzedy 50 mg (monthly)
    • Oral 3 mg (daily) ? Uzedy 75 mg (monthly)
    • Oral 4 mg (daily) ? Uzedy 100 mg (monthly)

    If switching from a risperidone long-acting intramuscular (IM) injection, start Uzedy at least 5 weeks after the last IM dose:

    • IM 25 mg (every 2 weeks) ? 50 mg (monthly)
    • IM 37.5 mg (every 2 weeks) ? 75 mg (monthly)
    • IM 50 mg (every 2 weeks) ? 100 mg (monthly)

    Ingredients

    The active ingredient in Uzedy is risperidone.

    Cautions

    Uzedy is not approved for dementia-related psychosis in older adults due to an increased risk of death and stroke/TIA.

    Contact your healthcare provider if you notice symptoms of or have concerns about the following:

    • Serious reactions, including neuroleptic malignant syndrome (NMS) and tardive dyskinesia.
    • Metabolic changes, including weight, blood sugar, and cholesterol/triglyceride changes.
    • Increased prolactin, which can negatively affect bone health when elevated long-term.
    • Low blood pressure.
    • Lowered white blood cells.
    • Seizures, swallowing problems, priapism, and difficulty regulating body temperature.

    Tell your provider if you have kidney or liver problems, a history of seizures, swallowing difficulties, or if you take other medicines, as some may affect risperidone levels.

    Avoid driving or operating heavy machinery until you know how Uzedy affects you (it may cause sleepiness and affect thinking and motor skills). Alcohol or sedating drugs are also not recommended.

    Contraindications

    Do not use this injection if you have a known hypersensitivity to risperidone, paliperidone, or any of the components in Uzedy.

    Side Effects

    Common Side Effects:

    • Sleepiness
    • Dizziness
    • Tremor
    • Restlessness
    • Stiffness
    • Muscle spasms
    • Stomach upset
    • Injection site reactions (e.g. itching)

    Serious Side Effects (less common):

    • Neuroleptic malignant syndrome (NMS)
    • Tardive dyskinesia (involuntary movements)
    • Metabolic changes (e.g. diabetes, lipid changes, weight gain)
    • Low white blood cell count
    • Seizures

    You may experience additional side effects of Uzedy (risperidone). Contact your doctor if you notice any persistent or concerning side effects from Uzedy, or if you have any additional questions about Uzedy’s cost, coverage, and more.

    Buy Uzedy injection from Canada Pharmacy at a low price!

    References

    • UZEDY (risperidone) extended-release injectable suspension, for subcutaneous use [prescribing information]. North Wales, PA: Teva Pharmaceuticals USA, Inc.; 2025. Retrieved Feb 2026. Prescribing Information .
    • UZEDY HCP website. Teva Neuroscience, Inc.; Retrieved Feb 2026. HCP Website .

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 15499

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