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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Velsipity (Etrasimod)

Brand

Velsipity (Etrasimod)

Prescription Required

Strength
Qty
2mg

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  • Product Details

    Description

    Livdelzi is a prescription medication used to help manage a chronic liver condition called primary biliary cholangitis (PBC) in adults. It’s used primarily when standard first-line treatments are insufficient or poorly tolerated.

    PBC causes small bile ducts in the liver to become damaged and inflamed, which leads to the buildup of bile and liver injury. Livdelzi addresses this issue by reducing bile-related inflammation. This may result in improved biochemical markers (e.g. ALP), reduced ongoing liver irritation, and overall symptom improvement.

    Fact Table

    Formula

    C26H26F3NO3

    License

    US FDA, EMA, Health Canada, TGA

    Bioavailability

    Absolute oral bioavailability not determined

    Legal status

    Rx-only

    Chemical Name

    [(3R)-7-{[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy}-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]acetic acid

    Elimination half-life

    Approximately 30 hours

    Dosage (Strength)

    2 mg tablet once daily; each tablet contains 2 mg etrasimod equivalent to 2.76 mg etrasimod arginine

    Pregnancy

    May cause fetal harm; avoid during pregnancy and consult a doctor

    Brands

    Velsipity

    Protein binding

    97.9%

    PubChem CID

    44623998

    MedlinePlus

    a623050

    ChEBI

    229230

    ATC code

    L04AE05

    DrugBank

    DB14766

    KEGG

    D10930; D10931 (etrasimod arginine)

    Routes of administration

    Oral

    Directions

    You can buy Livdelzi (10 mg oral tablets) at a low cost here at Canada Pharmacy. When starting Livdelzi, ensure you follow your healthcare provider’s directions closely. A typical dosing schedule consists of one tablet daily at approximately the same time. This medication can be taken with or without food.

    If you miss a dose, take it as soon as you remember. If it’s almost time for your next scheduled dose, proceed with your regular schedule. Do not double up.

    Ingredients

    The active ingredient in Livdelzi is seladelpar lysine.

    Cautions

    Before starting Livdelzi, tell your healthcare provider of any of the following:

    • Existing health conditions (e.g. symptoms of worsening liver symptoms, bile duct obstruction)
    • Medications, vitamins, or herbal supplements you’re taking (drug interactions may occur)
    • Allergies
    • Pregnancy and breastfeeding status. It’s unknown whether Livdelzi can harm an unborn baby or may pass into the breast milk.

    If you become pregnant while taking Livdelzi, inform your healthcare provider right away. You may participate in a pregnancy safety study for people who take Livdelzi during pregnancy. This helps collect information about maternal and infant health outcomes.

    While Livdelzi can improve key signs of liver disease (e.g. elevated alkaline phosphatase (ALP) and elevated bilirubin), it has not been confirmed whether Livdelzi improves survival or prevents worsening liver function.

    Livdelzi has not been studied or approved in children.

    Contraindications

    Do not take Livdelzi if you have advanced liver disease (decompensated cirrhosis), as the medication may cause worsening liver function in this case.

    Do not take Livdelzi if you have a bile duct obstruction.

    Side Effects

    Commonly reported Livdelzi side effects include headache, stomach or abdominal pain, nausea, bloating, and dizziness.

    More serious side effects include worsening liver problems (e.g. jaundice, abdominal swelling, vomiting blood, dark stools, or confusion), bone fractures, and increased liver enzymes.

    This is not a complete list of Livdelzi side effects. Consult your healthcare provider if you notice any persistent or concerning side effects of Livdelzi.

    Buy Livdelzi today from Canada Pharmacy at a low cost!

    References

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 15256

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