A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Verzenio is a prescription medicine used to treat certain patients with HR-positive, HER2-negative breast cancer. Verzenio is a targeted treatment known as a CDK4/6 inhibitor. It works inside the cell to block CDK4/6 activity and help stop the growth of cancer cells.
Take Verzenio exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Take the medicine at the same time each day, with or without food. Swallow the tablet whole and do not crush, chew, or break it. If you vomit shortly after taking Verzenio, do not take another dose. Wait until your next scheduled dose time to take the medicine again. Drink plenty of liquids while you are taking Verzenio. Abemaciclib can cause severe diarrhea, which can be life-threatening if it leads to dehydration or infection. If you have diarrhea while taking Verzenio: start taking anti-diarrhea medicine such as loperamide (Imodium) to quickly treat diarrhea. Drink extra fluids and call your doctor. Abemaciclib can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Store at room temperature away from moisture and heat.
The active ingredient in Verzenio is abemaciclib.
Verzenio can cause severe severe diarrhea, which can lead to dehydration or infection. Call your doctor right away if you have diarrhea. Drink extra fluids and start taking anti-diarrhea medicine such as loperamide (Imodium). Verzenio can cause blood clots, liver problems, or serious and sometimes fatal infections. Call your doctor right away if you have symptoms such as: fever, chills, easy bruising or bleeding, unusual tiredness, loss of appetite, right-sided upper stomach pain, chest pain, shortness of breath, rapid breathing, fast heartbeats, or pain or swelling in your arms or legs.
Get emergency medical help if you have signs of an allergic reaction to Verzenio: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have: • severe or ongoing diarrhea; • pain or burning when you urinate; • liver problems - right-sided upper stomach pain, loss of appetite, easy bruising or bleeding, feeling very tired; • low blood cell counts - fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; • signs of inflammation in the lungs - new or worsening cough, painful or difficult breathing, wheezing, feeling short of breath even while resting; or • signs of a blood clot - pain or swelling in an arm or leg, chest pain, fast heartbeats, feeling short of breath. Your cancer treatments may be delayed or permanently discontinued if you have certain side effects. Common Verzenio side effects may include: • diarrhea, nausea, vomiting, stomach pain; • loss of appetite; • hair loss; • infections; • feeling tired; • headache; or • low blood cell counts. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.