What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Vocabria (Cabotegravir)
Prescription Required
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Product Details
Description
Vocabria (cabotegravir) is a medication used to treat HIV-1 infection in adults and pediatric patients who are at least 12 years old and weigh 35 kg (77 lbs) or more.
Vocabria is also used to prevent exposure to HIV-1 infection in adults and adolescents who weigh 35 kg (77 lbs) or more and are at risk for HIV-1 infection.
Vocabria is available in a 30 mg tablet for oral administration.
Fact Table
Formula
C19H17F2N3O5
License
US DailyMed, EU EMA
Bioavailability
The oral tablet has a bioavailability of approximately 62%
Legal status
Rx-only
Chemical Name
Cabotegravir
Elimination half-life
For the oral tablet, it is approximately 40 to 48 hours.
Dosage (Strength)
30mg
Pregnancy
Consult Doctor
Brands
Vocabria is one of the brand names for cabotegravir. It may also be sold under other brand names
Protein binding
Cabotegravir has a high protein binding capacity, with approximately 99% binding to plasma proteins
PubChem CID
54713659
MedlinePlus
a621010
ChEBI
172944
ATC code
J05AJ04
DrugBank
DB11751
KEGG
D10548
Routes of administration
By Mouth
Directions
Take Vocabria exactly as prescribed by your doctor. Any questions or concerns can be referred to your doctor or pharmacist.
Your doctor will tell you how much Vocabria you should take and for how long you should take it. The typical dose is one tablet (Vocabria 30 mg) by mouth once daily with a meal. Your doctor may instruct you to take Vocabria with Edurant, another medication used to treat HIV-1.
Ingredients
Cabotegravir is the active ingredient in Vocabria. Inactive ingredients include hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate. The film-coating of the tablet contains hypromellose, polyethylene glycol, and titanium dioxide.
Contraindications
Do not take Vocabria if you are allergic to cabotegravir.
Do not take Vocabria with carbamazepine, oxcarbazepine, phenobarbital, phenytoin, rifampin, or rifapentine. Ask your doctor if you are unsure whether or not you take any of these medications.
Do not take Vocabria if you are HIV-1 positive for HIV-1 PrEP.
Cautions
- Before you start therapy with Vocabria, tell your doctor about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health conditions and past medical history
- Your pregnancy or breastfeeding status
- The use of Vocabria for HIV-1 PrEP should be part of comprehensive management to decrease the risk of acquiring HIV-1 infection.
- Serious allergic reactions may occur with the use of Vocabria. Patients should seek emergency care right away if they develop symptoms of an allergic reaction.
- Vocabria may cause liver problems.
- Vocabria may cause mood changes, including depression.
Side Effects
Common Vocabria side effects include fatigue, headache, diarrhea, nausea, dizziness, abnormal dreams, anxiety, problems sleeping, abdominal discomfort, abdominal distension, weakness, upper respiratory tract infection, sleepiness, and stomach pain. However, these are not all the side effects that can occur. Call your doctor right away if you have bothersome or persistent side effects.
Looking for a competitive Vocabria cost? You can buy Vocabria online at a competitive price and with a valid prescription from your doctor at Canada Pharmacy.
Reference:
Vocabria. Durham, NC: GlaxoSmithKline; 2023.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13893
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