What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Wegovy (Semaglutide)

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Brand

Wegovy (Semaglutide)

Prescription Required

Strength
Qty
0.25mg pens of 0.25mg / 0.5ml
0.5mg pen of 0.5mg / 0.5ml
1mg pens of 1mg / 0.5ml
1.7mg pens of 1.7mg / 0.75ml
2.4mg pens of 2.4mg / 0.75ml

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  • Product Details

    Description

    Wegovy (semaglutide) is a prescription medication primarily used for weight loss in adults and teenagers who are obese, as well as overweight adults with additional weight-related medical problems such as high blood pressure, type 2 diabetes, or high cholesterol. This medication works by regulating appetite and reducing calorie intake, aiding in both weight loss and weight management.

    Semaglutide, a synthetic version of the hormone glucagon-like peptide 1 (GLP-1) naturally released from the gut after eating, plays a crucial role in regulating blood sugar levels. This is particularly relevant for adults with an initial body mass index (BMI) of 30 kg/m2 or more (indicative of obesity) and 27 kg/m2 or more (indicative of overweight) in the presence of at least one weight-related comorbidity.

    Before you buy Wegovy, it is essential to discuss its effectiveness for weight loss and potential side effects with your healthcare provider.

    Fact Table

    Formula

    C187H291N45O59

    License

    EU EMA, US FDA

    Bioavailability

    89%

    Legal status

    Rx-Only

    Chemical Name

    Semaglutide

    Elimination half-life

    7 days

    Dosage (Strength)

    0.5mg pen of 0.5mg/0.5ml, 0.25mg pens of 0.25mg/0.5ml, 1mg pens of 1mg/0.5ml, 1.7mg pens of 1.7mg/0.75ml, 2.4mg pens of 2.4mg/0.75ml

    Pregnancy

    Not Recommended

    Brands

    Wegovy

    Protein binding

    More than 99%

    PubChem CID

    56843331

    MedlinePlus

    a618008

    ChEBI

    167574

    ATC code

    A10BJ06

    DrugBank

    DB13928

    KEGG

    D10025

    Routes of administration

    Subcutaneous

    Directions

    The initial administration of Wegovy injection starts with a dosage of 0.25 mg, administered weekly. This dosage remains constant throughout the initial four-week period. The dosage is systematically increased following a structured schedule:

    • In the second month, the dosage is 0.5 mg weekly
    • In the third month, the dosage progresses to 1.0 mg weekly
    • The fourth month sees a further increase to 1.7 mg weekly
    • From the fifth month onwards, the dosage stabilizes at the maintenance level of 2.4 mg weekly

    Wegovy is administered via subcutaneous injection, which can be done in the abdomen, thigh, or upper arm. It is critical to adhere strictly to the instructions provided to ensure the correct technique of self-injection is used. This medication should be injected beneath the skin and not into a muscle or vein for optimal efficacy.

    Ingredients

    The active ingredient in Wegovy is Semaglutide.

    Cautions

    Avoid this medication if you have a history of thyroid tumors, specifically Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia type 2 (MEN 2).

    Do not use it if you are allergic to semaglutide or any of its ingredients.

    Inform your doctor about any history of stomach or intestinal disorders, pancreatitis, kidney disease, diabetic retinopathy, or mental health issues.

    Be cautious about drug interactions, especially with diabetes medications.

    Monitor blood sugar levels for signs of hypo- or hyperglycemia.

    Never share an injection pen to prevent infection transmission.

    Use a new, sterile needle for each injection.

    Store the medication according to the instructions on the label, typically in a refrigerator at temperatures between 36°F to 46°F (2°C to 8°C). Avoid freezing and protect it from light. Discard the pen after use.

    Interactions

    Negative drug interactions may occur between Wegovy and 246 other prescription (Rx) or over-the-counter (OTC) medications. These include albuterol, amlodipine, aspirin, atorvastatin, bupropion, cyclobenzaprine, duloxetine (Cymbalta), famotidine, gabapentin, hydrochlorothiazide, hydroxyzine, ibuprofen, levothyroxine, lisinopril, losartan, meloxicam, metformin, montelukast, omeprazole, pantoprazole, prednisone, rosuvastatin, topiramate, trazodone, acetaminophen (Tylenol), Vitamin B12, Vitamin C, Vitamin D3, lisdexamfetamine (Vyvanse), and cetirizine (Zyrtec).

    Side Effects

    The most common side effects of Wegovy may include nausea, stomach (abdominal) pain, dizziness, stomach flu, diarrhea, headache, bloating, heartburn, vomiting, fatigue, belching, runny nose or sore throat, constipation, upset stomach, and gas.

    References

    Wegovy[Prescribing Information]. Bagsvaerd, Denmark: Novo Nordisk A/S; July 2023.


    Frequently Asked Questions about Wegovy (Semaglutide)


    What is Wegovy?

    Wegovy (semaglutide) injection 2.4 mg is a prescription medicine for adults and children aged 12 years or older with obesity or some adults with excess weight who also have weight-related medical problems. It is used alongside a reduced-calorie meal plan and increased physical activity.


    How does Wegovy work?

    It mimics a hormone that regulates appetite and food intake, helping you eat less and potentially lose weight.


    When can weight loss be expected with Wegovy?

    Weight loss timelines vary, and it is best to discuss expectations with a healthcare provider.


    What are common side effects?

    These include nausea, diarrhea, vomiting, constipation, stomach pain, headache, fatigue, dizziness, feeling bloated, belching, gas, stomach flu, heartburn, and runny nose or sore throat.


    Can I travel with Wegovy?

    Yes, but keep the Wegovy pen in your carry-on when flying to prevent freezing.


    How often is Wegovy taken?

    It must be taken once a week, any time of day, with or without food.


    Why are there different color pens?

    Each dose (0.25 mg, 0.5 mg, 1 mg, 1.7 mg, and 2.4 mg) comes in its own color pen.


    Should I take Wegovy with a meal?

    It can be taken with or without food.


    What if I miss a dose?

    If the next scheduled dose is more than 2 days away, take the missed dose as soon as possible. If it is less than 2 days away, skip the missed dose and continue with the regular schedule.


    How to dispose of used Wegovy pens?

    Use an FDA-cleared sharps disposal container or a sturdy household container with a tight-fitting lid and dispose of it as per local regulations.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14540

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