What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Wynzora ( Calcipotriene and Betamethasone dipropionate)
Prescription Required
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Product Details
Description
Wynzora (calcipotriene and betamethasone dipropionate) is a topical cream used to treat plaque psoriasis in patients who are at least 18 years old.
Calcipotriene is a vitamin D analog and betamethasone dipropionate is a corticosteroid.
Fact Table
Formula
C22H29FO5
License
US DailyMed
Bioavailability
Not Available
Legal status
RX-only
Chemical Name
Calcipotriene and Betamethasone dipropionate
Elimination half-life
36-54 hours
Dosage (Strength)
0.005% / 0.064% Cream
Pregnancy
Consult Doctor
Brands
Wynzora
Protein binding
Not Available
PubChem CID
9782
MedlinePlus
a682799
ChEBI
3077
ATC code
A07EA04
DrugBank
DB00443
KEGG
D00244
Routes of administration
Topical
Directions
Wynzora is supplied in a tube containing 0.005% calcipotriene and 0.064% betamethasone dipropionate. One gram of Wynzora cream consists of 50 mcg of calcipotriene and 0.644 mg of betamethasone dipropionate.
Follow the instructions that come with your prescription. If you have any questions or concerns about your prescription, talk to your doctor or pharmacist.
Wynzora cream should be applied to the affected areas of the skin one time a day for up to 8 weeks. Do not apply more than 100 grams of cream per week. Do not apply the cream to the face, groin, or armpit. Do not apply to thin skin. Do not get the cream in your mouth, eyes, or vagina. You should not use occlusive dressings unless your doctor has instructed you to do so.
Ingredients
The active ingredients contained in Wynzora cream are calcipotriene and betamethasone dipropionate.
Cautions
- Before you start treatment with Wynzora, it's important to talk to your doctor:
- About all the medications you take
- About your allergies
- About your health conditions
- About your pregnancy or breastfeeding status
- Wynzora cream can cause elevated calcium levels in the blood or urine.
- Wynzora cream can affect the endocrine system by causing reversible suppression of the hypothalamic pituitary-adrenal (HPA) axis and a decrease in the production of glucocorticoids during and after treatment. Your risk may be greater if you use a potent topical corticosteroid, use over a large portion of skin or to occlusive areas, use over a long period of time, have changes in your skin barrier, have liver problems, or you are young.
- Wynzora cream can increase the risk of vision problems such as cataracts and glaucoma.
Side Effects
The most common side effects of Wynzora cream include headache, upper respiratory tract infection, and irritation at the site of application. These are not all the possible side effects of Wynzora cream, so call your doctor right away if you develop side effects that concern you or won't go away.
Reference:
Wynzora (calcipotriene and betamethasone dipropionate) cream, for topical use. Charleston, SC: EPI Health, LLC.; 2021.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13652
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