What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Xerese (acyclovir/hydrocortisone) Cream


Xerese (acyclovir/hydrocortisone) Cream

Prescription Required

5g tube of 5% / 1%

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

We don't have this generic product yet!

Sign up to get exclusive coupon discounts and be the first to be notified when we have this product available.

  • Product Details


    Xerese is a prescription cold sore treatment medication that reduces the size of lesions and speeds up the healing time required for them. It also prevents initial cold sores from becoming ulcerative. A cold sore is ulcerative when it bursts and becomes a painful sore, but most people who use Xerese can stop the virus (herpes simplex) from progressing that far. Xerese cream for cold sores is easy to apply and is recommended for people who don't get sufficient relief from cold sores from OTC products like Anbesol.

    You can Xerese cream with a prescription at most pharmacies, and you'll likely have a lower Xerese cream cost when you order medication online from Canada Pharmacy.


    Xerese cold sore cream should be applied as soon as you see signs of a cold sore developing.

    Wash hands before and after use.

    Apply the cream 5 times a day for the first 5 days of treatment. After that, apply cream less frequently depending on reduction of cold sore until you completely get rid of cold sores.

    Do not cover treatment area with bandage after application. Do not apply makeup (lipstick) to lips when treating a cold sore with Xerese.


    The active ingredients in Xerese are Acyclovir and Hydrocortisone.


    For topical use in and around the mouth only, not to be applied anywhere else on the body.

    For use with ages 6 and up.

    Use with caution if pregnant or nursing and discuss this with your doctor before starting with Xerese.

    Do not use other skin care products (including sunscreen) on affected areas while treating a cold sore with Xerese.

    Do not exceed maximum dosage regulation of 5 applications per day. If product is not working effectively speak with your doctor again.


    There is the possibility of drug interaction risks between Xerese and these RX medications - acetaminophen / tramadol / alprazolam amoxicillin / clavulanate / Augmentin (amoxicillin / clavulanate) / Azithromycin / baclofen / Benadryl (diphenhydramine) / bupropion / cetirizine / clonazepam / Cymbalta (duloxetine) / Diflucan (fluconazole) / Flexeril (cyclobenzaprine) / hydrocortisone topical / magnesium citrate / Synthroid (levothyroxine) / Tylenol with Codeine #3 (acetaminophen / codeine) / valacyclovir / Valtrex (valacyclovir) / zolpidem.

    Tell your doctor about all medications you are currently taking before getting your prescription and proceeding to buy Xerese cream.

    Side Effects

    Side effects from Xerese are uncommon, but some people may experience drying or flaking of the skin, burning or tingling, erythema, pigmentation changes or inflammation of the skin. If any of these side effects are observed, then discontinue use and speak with your doctor again to discuss other RX medication for cold sore treatment.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 12993

  • Product Reviews


Please wait while the page is loading. Do not hit refresh or the browser back button to avoid any loss of information.

If you have any questions or concerns, please contact our Customer Service team via the chat option on our website or calling us toll free at: 1-800-891-0844