A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
XULTOPHY (insulin degludec and liraglutide) is a prescription medication prescribed to improve glycemic control in people who have type 2 diabetes mellitus.
People with type 2 diabetes mellitus still produce insulin, but their bodies have become resistant, requiring extra insulin. Insulin is the primary hormone that lowers blood sugar to normal levels.
Directions
Inject XULTOPHY subcutaneously once daily at the same time each day. XULTOPHY can be given with or without food.
XULTOPHY is dosed based on how much insulin a person normally uses. The possible starting doses are:
10 units insulin degludec and 0.36 mg liraglutide once daily
16 units insulin degludec and 0.58 mg liraglutide once daily
The maximum daily dose of XULTOPHY is 50 units insulin degludec and 1.8 mg liraglutide.
Ingredients
XULTOPHY contains two active ingredients: long-acting insulin and a GLP-1 receptor agonist.
Insulin degludec is a long-acting insulin that lasts about 24 hours for most patients.
Liraglutide is a GLP-1 receptor agonist that works by slowing down the gastrointestinal tract and by causing the pancreas to release extra insulin.
Interactions
Tell your doctor or pharmacist if you are taking any medications that mask the signs of hypoglycemia:
Beta-blockers
Clonidine
Guanethidine
Reserpine
The following drugs can affect the blood sugar of people with type 2 diabetes mellitus:
Alcohol
Atypical Antipsychotics
Corticosteroids
Disopyramide
Diuretics
Estrogens/Progesterones
Fibrates
Fluoxetine
Isoniazid
Lithium
Monoamine Oxidase Inhibitors (MAOIs)
Niacin
Oral antidiabetic agents
Pentoxifylline
Phenothiazine derivatives
Pramlintide
Propoxyphene
Protease inhibitors
Salicylates
Somatostatin Analogues
Somatropin
Sulfonamide Antibiotics
Sympathomimetic agents
Thyroid replacement medication
Since liraglutide slows down the gastrointestinal tract, use caution if you are taking the following medications:
Acetaminophen (Tylenol)
Antibiotics
Oral contraceptives
Cautions
XULTOPHY cannot be used by anyone with a history of Medullary Thyroid Cancer (MTC). It is also contraindicated for people with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Rotate injection sites to avoid lipodystrophy.
Do not use XULTOPHY in an insulin pump.
Side Effects
The most common adverse reactions from XULTOPHY may include:
Allergic reactions
Diarrhea
Headache
Hypoglycemia
Nausea
Upper respiratory tract infection
Buy XULTOPHY insulin/GLP-1RA combination online from Canda Pharmacy.
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.