What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Aspirin
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Product Details
Description
Aspirin is a medication available as a prescription or, more commonly, over-the-counter (OTC). It is commonly used OTC to treat mild headaches and other painful conditions. Prescription aspirin is used to treat cardiovascular diseases that require platelet inhibition.
The common uses for aspirin include:
- Acute Coronary Syndrome (including heart attack)
- Carotid artery stenting
- Colorectal cancer risk reduction
- Migraine
- Percutaneous coronary intervention for stable ischemic heart disease
- Pericarditis
- Preeclampsia prevention
- Preventing atherosclerotic cardiovascular disease
- Prevention of blood clot is polycythemia vera
- Valvular heart disease
- Venous thromboembolism prevention
Aspirin works by blocking signal molecules in the bloodstream that contribute to pain signals and clot formation. Taking aspirin reduces the risk of clots and also lowers the feeling of pain.
Fact Table
Formula
C9H8O4
License
US FDA, EU EMA
Bioavailability
80–100%
Legal status
Rx-only
Chemical Name
acetylsalicylic acid
Elimination half-life
2–3 hours
Dosage (Strength)
81mg, 325mg
Pregnancy
Consult Doctor
Brands
Bayer Aspirin
Protein binding
80–90%
PubChem CID
2244
MedlinePlus
a682878
ChEBI
15365
ATC code
A01AD05
DrugBank
DB00945
KEGG
D00109
Routes of administration
By mouth
Directions
Take aspirin exactly as prescribed by your doctor.
For cardiovascular health, the adult aspirin dose is 81-235 mg by mouth once daily.
For pain, the normal dose of aspirin is 325-975 mg by mouth every four to six hours as needed.
Ingredients
The active ingredient in aspirin is salicylic acid.
Interactions
Tell your doctor and pharmacist about all of the medications you are taking. Common drug-drug interactions may include:
- Apixaban
- Carbonic anhydrase inhibitors
- Cox-2 selective enzymes
- Dabigatran
- Enoxaparin
- Ginkgo Biloba
- Ketorolac
- Methotrexate
- Rivaroxaban
- Sincalide
- Ticagrelor
- Varicella-containing vaccine
- Warfarin
Cautions
Tell your doctor if you have a history of gastrointestinal bleed before taking aspirin.
Children and adolescents with flu-like symptoms or chickenpox should not use aspirin.
Ask your doctor and pharmacist for a full list of precautions that apply to you.
Side Effects
Common side effects with aspirin include:
- Gastritis
- Headache
- Hemorrhage
- Hepatotoxicity
- Increased serum creatinine
- Nausea
- Renal insufficiency
- Reye's syndrome
- Skin rash
- Stomach pain
- Ulcer
- Vomiting
References
Aspirin [package insert]. Whippany, NJ: Bayer; 2020.
Frequently Asked Questions about Aspirin
What is aspirin?
Aspirin is a common over-the-counter medication that belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily used as a pain reliever and fever reducer.
How does aspirin work?
Aspirin works by inhibiting the production of certain chemicals in the body called prostaglandins. These chemicals are involved in pain, inflammation, and fever. By reducing prostaglandin production, aspirin helps alleviate these symptoms.
What are the common uses of aspirin?
Aspirin is commonly used for pain relief, reducing fever, and relieving minor aches and pains. It is also prescribed by doctors to prevent blood clots, heart attacks, and strokes in certain individuals.
Is aspirin safe for everyone?
No, aspirin is not safe for everyone. It is not recommended for individuals with certain medical conditions or allergies, especially those with bleeding disorders, stomach ulcers, or aspirin allergies. It can also interact with other medications, so it's important to consult a healthcare professional before using it.
Can aspirin be given to children?
Aspirin should generally be avoided in children and teenagers with viral infections like the flu or chickenpox due to the risk of Reye's syndrome, a rare but serious condition. Acetaminophen or ibuprofen are usually preferred for pain and fever in this age group.
What are the potential side effects of aspirin?
Common side effects of aspirin can include stomach irritation, indigestion, and heartburn. In some cases, it may lead to more serious side effects such as gastrointestinal bleeding or allergic reactions. It's crucial to use aspirin as directed and seek medical attention if you experience severe side effects.
Can aspirin be taken with other medications?
Aspirin can interact with various medications, including blood thinners, anti-inflammatory drugs, and certain supplements. Always consult your healthcare provider or pharmacist before taking aspirin alongside other medications to avoid potential complications.
Can aspirin be used during pregnancy or while breastfeeding?
Pregnant and breastfeeding individuals should consult their healthcare provider before using aspirin. In some cases, it may be recommended, but it should be used under medical supervision due to potential risks to the fetus or infant.
Can aspirin be addictive?
Aspirin is not considered addictive because it does not produce the same effects as drugs that are known to be addictive. However, it should be used responsibly and according to the recommended dosage instructions.
What should I do if I accidentally take too much aspirin?
If you suspect an overdose or experience symptoms like ringing in the ears, dizziness, nausea, vomiting, or difficulty breathing after taking aspirin, seek immediate medical attention. An overdose of aspirin can be serious and even life-threatening.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1940
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