What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Auryxia (Ferric Citrate)
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Product Details
Description
Auryxia (Ferric Citrate) is a phosphate binder and iron replacement product. It is known chemically as ferric citrate and works by binding phosphate in the digestive tract. This action helps reduce phosphate levels in the blood. Healthcare providers often prescribe Auryxia for patients with chronic kidney disease (CKD) to manage hyperphosphatemia or iron deficiency anemia.
Directions
The starting dosage is typically one or two pills three times a day with meals, depending on the condition being treated. The dosage may be gradually increased to a maximum dosage of 12 tablets per day. It’s important to swallow the tablets whole. Do not chew or crush them, as this can cause discoloration of the mouth and teeth.
Ingredients
The active ingredient in Auryxia is Ferric Citrate.
Contraindications
Avoid taking or using this medication if any of the following apply:
- Iron overload syndromes (e.g., hemochromatosis)
- Known allergies to ferric citrate or any other component in Auryxia
- Existing conditions that cause high levels of iron in the blood
Cautions
- Before starting treatment with Auryxia, be sure to inform your healthcare provider about the following:
- Any medical conditions you currently have
- Any allergies
- All medications you are currently taking
- Whether you are pregnant or breastfeeding
- Auryxia can lead to significant increases in iron levels. Monitor iron levels like serum ferritin and TSAT before and during treatment. If you're receiving intravenous iron, you might need to adjust its dosage or stop it altogether due to Auryxia's iron content.
- Auryxia can be extremely dangerous if ingested by children. There have been cases of fatal poisoning in children under six from accidental iron ingestion. Keep Auryxia out of reach of children to avoid accidental ingestion and overdose.
Side Effects
Common side effects of Auryxia include diarrhea, changes in stool color, nausea, constipation, vomiting, and sometimes coughing. These effects are usually manageable but can be uncomfortable.
While rare, Auryxia can cause serious issues such as high potassium levels, which might affect heart health. It may also lead to severe gastrointestinal problems that could lead to discontinuation of the medication. If you experience severe side effects like intense stomach pain or persistent gastrointestinal problems, it's important to seek medical attention immediately. These serious conditions are uncommon but need prompt medical evaluation.
References
- Auryxia (Ferric Citrate) Product Monograph. Cambridge, MA: Akebia Therapeutics, Inc.; 2024.
- Auryxia (Ferric Citrate) Drug Label Information. Cambridge, MA: Akebia Therapeutics, Inc.; 2024.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14911
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