What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Bactroban 2% cream (Mupirocin)
Prescription Required
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Product Details
Description
Bactroban is a prescription cream that is used for the treatment of bacterial infection of the skin, often of the nasal passages. Your doctor may also prescribe it to treat infections that are on different areas of the body.
Bactroban works by preventing the replication of bacteria that cause infection. Typically, the body can fight off bacteria on its own. But if bacteria can multiply faster than the body can manage, Bactroban can slow down the infection so that the body can clear it.
Bactroban works by blocking a protein called bacterial isoleucyl transfer-RNA synthetase. Blocking this protein prevents the formation of critical proteins, causing the bacterial cells to die.
Fact Table
Formula
C26H44O9
License
US FDA
Bioavailability
100%
Legal status
CA OTC, US Rx Only
Chemical Name
Mupirocin
Elimination half-life
20 to 40 minutes
Dosage (Strength)
2%
Pregnancy
Consult Doctor
Brands
Bactroban
Protein binding
97%
PubChem CID
446596
MedlinePlus
a688004
ChEBI
7025
ATC code
D06AX09
DrugBank
DB00410
KEGG
D01076
Routes of administration
Topical
Directions
The usual dosage is 0.5 grams applied to the affected area 2-3 times daily for 5-14 days. Do not stop taking this medication before finishing the entire course of treatment.
Ingredients
The active ingredient in Bactroban is mupirocin.
Interactions
There are no known significant interactions.
Do not mix Bactroban with other topical medications or with lotions, creams, or ointments. Allow the cream to absorb into the skin for at least 15-30 minutes before applying another topical preparation.
Cautions
If irritation occurs at the site, stop using Bactroban and tell your doctor.
Do not use this cream for longer than prescribed as it may increase the risk of bacterial resistance.
Tell your doctor if you have a history of kidney problems.
Some formulations of Bactroban contain benzyl alcohol or polyethylene glycol.
Side Effects
Common side effects can include:
- Aphthous Stomatitis
- Blepharitis
- Cellulitis
- Clostridioides Difficile-Associated Diarrhea
- Contact Dermatitis
- Cough
- Dermatitis
- Diarrhea
- Dizziness
- Dysgeusia
- Epistaxis
- Erythema
- Headache
- Hypersensitivity Reaction
- Increased Wound Secretion
- Local Pain
- Localized Burning
- Localized Edema
- Localized Tenderness
- Nausea
- Otalgia
- Pharyngitis
- Pruritus
- Respiratory Congestion
- Rhinitis
- Skin Rash
- Stinging Sensation
- Urticaria
- Wound Infection
- Xeroderma
- Xerostomia
References
- Bactroban Cream [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2015.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 2211
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