What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Clavamox (amoxicillin and clavulanate potassium)
Prescription Required
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Product Details
Description
Clavamox (amoxicillin and clavulanate potassium) is a prescription antibiotic for dogs and cats. In dogs, it treats skin and soft tissue infections like wounds, abscesses, cellulitis, and pyoderma, as well as gum infections. In cats, it treats skin and soft tissue infections and urinary tract infections. It contains amoxicillin, which helps kill bacteria, and clavulanate potassium, which helps amoxicillin work against more types of bacteria. Clavamox comes as chewable tablets or a liquid called Clavamox Drops.
Fact Table
Formula
C24H27KN4O10S (anhydrous combination)
License
US FDA veterinary: NADA 055-099 (chewable tablets); NADA 055-101 (oral suspension)
Bioavailability
Cats, oral: amoxicillin 75.57%; clavulanic acid 98.15%
Legal status
Prescription-only veterinary medicine; use by or on the order of a licensed veterinarian
Chemical Name
Amoxicillin trihydrate and clavulanate potassium
Elimination half-life
Cats, oral: amoxicillin 1.24 ± 0.28 hours; clavulanic acid 0.63 ± 0.16 hours
Dosage (Strength)
Chewable tablets: 62.5 mg (50/12.5 mg), 125 mg (100/25 mg), 250 mg (200/50 mg), 375 mg (300/75 mg); drops: 62.5 mg/mL (50/12.5 mg/mL)
Pregnancy
Safety in pregnant or breeding animals has not been determined; consult a veterinarian
Brands
Clavamox Chewable, Clavamox Drops
Protein binding
Amoxicillin approximately 18%; clavulanic acid approximately 25% (human serum reference)
PubChem CID
23665637
MedlinePlus
a685024
ChEBI
51254 (amoxicillin trihydrate); 48947 (clavulanic acid)
ATC code
QJ01CR02 (ATCvet); J01CR02 (human ATC)
DrugBank
DB01060 (amoxicillin); DB00766 (clavulanic acid)
KEGG
D06485
Routes of administration
Oral (chewable tablet or oral suspension)
Directions
Give Clavamox exactly as prescribed by a veterinarian. The usual dose for dogs is 6.25 mg per pound of body weight twice daily, or about 1 mL per 10 pounds twice daily when giving the drops. For cats, the usual dose is 62.5 mg twice daily, equal to one 62.5 mg tablet or 1 mL of the drops twice daily.
Most skin infections are treated for 5 to 7 days, or for 48 hours after symptoms are gone. Some deeper skin infections in dogs may need up to 21 days, and cat urinary tract infections may need 10 to 14 days or longer. However, treatment should not last more than 30 days. If your dog does not improve after 5 days, or your cat does not improve after 3 days, contact your veterinarian.
Keep chewable tablets in the foil until use, and make sure your pet eats the full tablet. After mixing the drops, refrigerate them, shake well before each dose, and throw away any unused medicine after 10 days.
Ingredients
The active ingredients in Clavamox are amoxicillin (as amoxicillin trihydrate) and clavulanic acid (as clavulanate potassium).
Cautions
Before giving this medication, you may want to consult a veterinarian about the following:
- Any existing health conditions
- Any allergies
- A list of all medications currently being taken
Clavamox is for use in dogs and cats only, and its safety in pregnant or breeding animals has not been determined.
Not for human use. Keep this medication out of reach of children, and store the tablets in a secure location out of reach of pets to prevent accidental ingestion or overdose.
People who are sensitive to penicillins or cephalosporins should avoid direct skin contact with this product, as it may cause allergic reactions in sensitized individuals.
Contraindications
Avoid giving this medication if the animal has a history of an allergic reaction to any penicillins or cephalosporins.
Side Effects
Common side effects of Clavamox may include:
- Loss of appetite
- Tiredness or low energy
- Vomiting
- Diarrhea
Because Clavamox contains a penicillin (amoxicillin), it may cause allergic reactions in some animals. Contact a veterinarian immediately if the pet shows signs of an allergic reaction, such as swelling of the face, hives, or trouble breathing, as emergency treatment may be needed.
References
- Clavamox Chewable Drug Label Information . Kalamazoo, MI: Zoetis Inc.; 2024.
- Clavamox Drops Drug Label Information . Kalamazoo, MI: Zoetis Inc.; 2024.
Frequently Asked Questions about Clavamox
What is Clavamox?
Clavamox is a prescription veterinary antibiotic containing amoxicillin and clavulanate potassium. Amoxicillin kills susceptible bacteria, while clavulanate helps prevent certain bacteria from breaking down the antibiotic.
What is Clavamox used for?
Clavamox is used in dogs and cats to treat susceptible bacterial infections. Common uses include infected wounds, abscesses, cellulitis, skin infections, and other soft-tissue infections. It may also treat periodontal infections in dogs and certain urinary tract infections in cats.
Does Clavamox treat viruses or fungal infections?
No. Clavamox treats specific bacterial infections and does not work against viruses, fungi, or parasites. Using antibiotics when they are not needed may contribute to antibiotic resistance.
How is Clavamox given?
Clavamox is given by mouth as a chewable tablet or liquid suspension. The correct dose and treatment duration depend on the animal’s species, weight, infection, formulation, and response, so the veterinarian’s directions should be followed exactly.
Should Clavamox be given with food?
Clavamox may generally be given with a small amount of food, which can help reduce stomach upset. Make sure the animal consumes the entire prescribed dose.
What are the common side effects of Clavamox?
The most commonly reported effects include reduced appetite, lethargy, vomiting, and diarrhea. Contact the veterinarian if these effects are severe, persistent, or accompanied by dehydration, weakness, or blood in the stool.
Can Clavamox cause an allergic reaction?
Yes. Animals allergic to penicillins or cephalosporins should not receive Clavamox. Facial swelling, hives, breathing difficulty, collapse, or sudden severe vomiting may indicate a serious allergic reaction requiring immediate veterinary attention.
What should I do if a dose is missed?
Give the missed dose when remembered unless it is nearly time for the next scheduled dose. Do not give two doses together unless specifically directed by the veterinarian.
How should Clavamox be stored?
Chewable tablets should be stored in a cool, dry place at or below 25°C or 77°F and kept in their packaging until use. Reconstituted Clavamox liquid must be refrigerated, shaken before dosing, and discarded after 10 days.
Can treatment be stopped when the pet feels better?
Clavamox should be given for the full period prescribed unless the veterinarian changes the treatment. Stopping early may allow the infection to return and may encourage antibiotic resistance.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13665
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