What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Colofac (Mebeverine)


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Generic Equivalent - Colofac (Mebeverine)

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  • Product Details


    Colofac (Mebeverine) is an antispasmodic medication used to treat irritable bowel syndrome and other related conditions. It can help relieve symptoms like bloating, diarrhea, gas, and pain in the lower abdomen. Mebeverine works by targeting specific muscles in the intestinal wall, causing them to relax and easing gastrointestinal spasms to alleviate discomfort.

    Fact Table




    US FDA



    Legal status


    Chemical Name


    Elimination half-life

    2 hours

    Dosage (Strength)



    Consult Doctor



    Protein binding


    PubChem CID



    Not Assigned


    Not Assigned

    ATC code






    Routes of administration

    By mouth


    The standard dosage of Colofac is 135 mg three times daily. It is typically recommended to take the doses around 20 minutes before the three main meals of the day. The maximum dosage is three tablets per day.

    The tablets should be swallowed whole with a glass of water. Do not chew the tablets. If symptoms improve after several weeks of use, a healthcare provider may gradually reduce the dosage.


    Each Colofac tablet contains 135 mg of Mebeverine as the active ingredient. In addition to the active ingredient, Colofac tablets may contain inactive ingredients that contribute to the tablet's structure and stability. These excipients include lactose monohydrate, potato starch, povidone, purified talc, magnesium stearate, sucrose, gelatine, and acacia.


    Avoid taking or using this medication if you have a hypersensitivity to Mebeverine or any of the excipients in the drug's composition.


    • If you plan to take Colofac, consider discussing with your doctor:
      • Other medications you are taking
      • Existing medical conditions
      • Known or suspected allergies you may have
    • Colofac should be used with caution in people with cardiac dysrhythmia, atrioventricular heart block, angina, or severe ischaemic heart disease.
    • Tell your doctor if you have liver or kidney problems before taking Colofac, as these problems may affect how the medication is processed in the body.
    • If you suspect you have lactose intolerance resembling irritable bowel syndrome symptoms, be cautious as each Colofac tablet contains 80 mg of lactose.
    • In cases of rare genetic issues related to galactose metabolism, such as Lapp lactase deficiency or glucose-galactose malabsorption, Colofac is not recommended.
    • For those with uncommon hereditary conditions like fructose intolerance, glucose-galactose malabsorption, or sucrase-isomaltase insufficiency, avoid using this medication due to its sucrose content.

    Side Effects

    Colofac may cause certain side effects. Common side effects may include mild skin rash, heartburn, indigestion, constipation, dizziness, insomnia, and headache. These side effects are usually mild and tend to pass quickly as the body adjusts to the medication.

    In rare cases, more serious side effects may occur and require immediate medical attention. If you experience signs or symptoms of an allergic reaction, such as hives, swelling of the face or throat, or trouble breathing, seek immediate medical attention.


    1. Colofac 135 mg Tablets Summary of Product Characteristics. Hertfordshire, UK: Mylan; 2016
    2. Colofac (Mebeverine) Package Leaflet. Hertfordshire, UK: Mylan; 2016
    3. Colofac (Mebeverine) Data Sheet. Ellerslie, NZ: Viatris; 2022

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 11312

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