Description
What is Creon used for?
Creon (Pancreatic Enzyme)
This particular medicine helps you to digest fats, proteins, and sugar. This medicine contains a combination of the substances, namely, lipase, protease, and amylase. These particular enzymes are produced by the pancreas, and they help in digestion. The lack of sufficient enzymes in your body could be due to a number of factors. These include cystic fibrosis, chronic inflammation of the pancreas, or the blocking of the pancreatic duct. The lack of enzymes in the body due to these factors can then be compensated by taking Creon.
This pancreatic enzyme supplement is easily available online. You can buy Creon medication from Canada Pharmacy online.
| Fact Table |
| Formula |
Not applicable as Creon is a mixture of digestive enzymes including lipases, proteases, and amylases |
| License |
FDA approved |
| Bioavailability |
Not applicable (local effect in the gastrointestinal tract) |
| Legal status |
Prescription drug (Rx) |
| Chemical Name |
Pancrelipase (a combination of lipase, protease, and amylase enzymes) |
| Elimination half-life |
Not applicable (enzymes act locally in the gastrointestinal tract and are not systemically absorbed in a significant amount) |
| Dosage (Strength) |
3,000; 6,000; 12,000; 24,000; and 36,000 USP units of lipase |
| Pregnancy advice |
Generally considered safe but should only be used if clearly needed and prescribed by a healthcare provider |
| Brands |
Creon |
| Protein binding |
Not applicable |
| PubChem CID |
Not available as this applies to single chemical entities |
| MedlinePlus |
a601112 |
| ChEBI |
Not available |
| ATC code |
A09AA02 |
| DrugBank |
DBSALT002080 |
| KEGG |
Not available |
| Routes of administration |
Oral |
Directions
Creon medication should be taken strictly as your doctor has prescribed it to you. Keep in mind the fact that do not switch brands without first informing your doctor.
This particular medicine should be taken with your food. Do not hesitate to ask any questions that you have and also bear in mind that be extra careful in following the instructions if you are giving this medicine to your children.
It may also be given with a stomach acid reducer such as Nexium, Prevacid, Prilosec, or Protonix.
Do not crush or chew the tablet. Take the capsule whole with a glass of water. However, if you do open the capsule and sprinkle the powder over pudding to take it, take it immediately. Do not keep it for later use. Do not mix it with formula milk or breastmilk when giving it to children. Do not inhale the powder or let it touch your skin as it may cause inflammation.
It is recommended that you take the medicine whole and follow the instructions carefully.
Ingredients
The active ingredient is pancrelipase, a combination of the digestive enzymes lipase, protease, and amylase. The inactive ingredients in the enteric-coated pellets may include cetyl alcohol, dimethicone, hypromellose phthalate, polyethylene glycol, and triethyl citrate. The capsule shells may contain gelatin, hypromellose, carrageenan, potassium chloride, sodium lauryl sulfate, titanium dioxide, and iron oxide or FD and C coloring agents.
Cautions
Before using this medication, you may want to consult a healthcare provider about the following:
- Any existing health conditions
- Any allergies
- A list of all medications currently being taken
A rare but serious bowel condition called fibrosing colonopathy, or narrowing of the large intestine, has been linked to high doses of pancreatic enzyme products taken over a long time, mostly in children with cystic fibrosis. Use the lowest effective dose, do not exceed the recommended limits, and tell your healthcare provider about ongoing abdominal pain, bloating, vomiting, or changes in bowel habits.
The capsules and pellets can irritate the lining of the mouth if they are held in the mouth, crushed, or chewed. Swallow them whole with plenty of liquid, and if you sprinkle the pellets on food, take the mixture right away and do not keep it for later.
High doses have been associated with high uric acid levels in the blood. If you have gout, kidney problems, or high uric acid, your healthcare provider may monitor your uric acid levels.
Creon is made from pork, or porcine, pancreas. People with a known allergy to pork proteins should be monitored, and there is a low but potential risk of viral transmission from the animal source, although no cases linked to Creon have been reported.
Serious allergic reactions, including anaphylaxis, asthma, hives, and itching, have been reported with pancreatic enzyme products. Tell your healthcare provider about any past reaction, and seek care if a reaction occurs.
Tell your healthcare provider if you are pregnant or breastfeeding. Store at room temperature up to 25°C (77°F), protect from moisture, and keep out of reach of children.
Contraindications
There are no contraindications for Creon in the drug label.
Side Effects
Common side effects of Creon include:
- Vomiting
- Abdominal, or stomach, pain
- Gas, also called flatulence, and frequent or abnormal bowel movements
- Dizziness
- Cough
- High or low blood sugar, in people with chronic pancreatitis or after pancreatic surgery
Stop taking Creon and get medical help if you have signs of a serious allergic reaction, such as swelling of the face, lips, tongue, or throat, trouble breathing or wheezing, hives, or severe itching. Contact your healthcare provider if you develop severe or unusual stomach pain, bloating, or a change in your bowel movements, which could be signs of fibrosing colonopathy.
References
Creon Highlights of Prescribing Information. North Chicago, IL: AbbVie Inc.; 2024.
Creon Drug Label Information. North Chicago, IL: AbbVie Inc.; 2026.
About Dr. Gerardo Sison (Page Author)
Dr. Sison graduated with honors from the University of Florida. He began his career in pharmacy counseling patients in a community setting and later served in hospitals and clinics. He has also worked in medication therapy management services. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 9748