What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Cytoxan (Cyclophosphamide)

Also Known as procytox


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Generic Equivalent - Cytoxan (Cyclophosphamide)

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  • Product Details


    Cytoxan is a prescription chemotherapy medication used to treat a variety of cancer. It should only be prescribed by an oncologist in a controlled setting.

    Fact Table




    US DailyMed


    More than 75% (by mouth)

    Legal status


    Chemical Name


    Elimination half-life

    3 –12 hours

    Dosage (Strength)

    50mg (Generic)


    Consult Doctor



    Protein binding

    More than 60%

    PubChem CID






    ATC code






    Routes of administration

    By mouth


    Take Cytoxan exactly as prescribed by your doctor. The dose varies based on your chemotherapy regimen, weight, and total Cytoxan exposure.


    The active ingredient in Cytoxan is cyclophosphamide.


    Tell your doctor about all medications you are taking, including:

    • Abrocitinib
    • Baricitinib
    • BCG Products
    • Brivudine
    • Cladribine
    • Dengue Tetravalent Vaccine (Live)
    • Deucravacitinib
    • Dipyrone
    • Etanercept
    • Fexinidazole
    • Filgotinib
    • Mumps- Rubella- or Varicella-Containing Live Vaccines
    • Natalizumab
    • Pimecrolimus
    • Poliovirus Vaccine (Live/Trivalent/Oral)
    • Ruxolitinib (Topical)
    • Tacrolimus (Topical)
    • Talimogene Laherparepvec
    • Tertomotide
    • Tofacitinib
    • Typhoid Vaccine
    • Upadacitinib
    • Yellow Fever Vaccine


    Tell your doctor if you have a history of kidney or liver problems before starting this medication.

    Some Cytoxan formulations may contain ethyl alcohol, impairing the ability to drive or operate heavy machinery.

    Ask your doctor for a full list of precautions.

    Side Effects

    Common interactions with Cytoxan may include:

    • Acute myocardial infarction
    • Acute pancreatitis
    • Ageusia
    • Alopecia
    • Amenorrhea
    • Anemia
    • Atrial fibrillation
    • Atrial flutter
    • Azoospermia
    • Bladder carcinoma
    • Bladder disease
    • Bone marrow depression
    • Bradycardia
    • Cardiac tamponade
    • Cardiogenic shock
    • Cardiomyopathy
    • Changes in nails
    • Chest pain
    • Cholestasis
    • Colitis
    • Constipation
    • Cystitis
    • Decreased serum glucose
    • Defective oogenesis
    • Defective spermatogenesis
    • Dermatitis
    • Dysgeusia
    • Edema
    • Enteritis
    • Erythema multiforme
    • Erythema of skin
    • Febrile neutropenia
    • Fluid retention
    • Flushing
    • Gastrointestinal hemorrhage
    • Heart failure
    • Hematuria
    • Hot flash
    • Hyperhidrosis
    • Hypertension
    • Hyponatremia
    • Hypotension
    • Increased lactate dehydrogenase
    • Increased serum glucose
    • Infertility
    • Infrequent uterine bleeding
    • Leukopenia
    • Malignant neoplasm of thyroid
    • Myelodysplastic syndrome
    • Myocarditis
    • Nausea
    • Nephrogenic diabetes insipidus
    • Neutropenia
    • Neutropenic typhlitis
    • Oligospermia
    • Oral mucosa ulcer
    • Palpitations
    • Parotitis
    • Pericardial effusion
    • Pericarditis
    • Peripheral ischemia
    • Premature labor
    • Prolonged QT interval on ECG
    • Pruritus
    • Pulmonary embolism
    • Pulmonary hemorrhage
    • Pyelitis
    • Skin abnormalities related to radiation recall
    • Skin blister
    • Skin rash
    • Skin toxicity
    • Stevens-Johnson syndrome
    • Stomatitis
    • Supraventricular cardiac arrhythmia
    • Tachycardia
    • Testicular atrophy
    • Toxic epidermal necrolysis
    • Toxic nephrosis
    • Ureteral disease
    • Urticaria
    • Vasculitis
    • Venous thrombosis
    • Ventricular arrhythmia
    • Vomiting
    • Water intoxication


    1. Cytoxan [package insert]. Columbus, Ohio: Roxane; 2007.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1450

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