Description
Minipress is the brand name for the prescription drug prazosin. Prazosin is used to treat high blood pressure.
High blood pressure (or hypertension) is a condition where the blood is pushing too forcefully on the walls of the blood vessels. High pressure can lead to small tears in the vessels and damage to the organs. Left untreated, high blood pressure can lead to cardiovascular events like a heart attack or stroke.
Minipress works by relaxing blood vessels and reducing the pressure on the vessel walls. It belongs to a group of medications called alpha-blockers.
Fact Table |
Formula |
C19H21N5O4 |
License |
US FDA |
Bioavailability |
~60% |
Legal status |
Rx-only |
Chemical Name |
Prazosin |
Elimination half-life |
2–3 hours |
Dosage (Strength) |
1mg, 5mg |
Pregnancy |
Consult Doctor |
Brands |
Minipress, Vasoflex |
Protein binding |
97% |
PubChem CID |
4893 |
MedlinePlus |
a682245 |
ChEBI |
8364 |
ATC code |
C02CA01 |
DrugBank |
DB00457 |
KEGG |
D08411 |
Routes of administration |
By mouth |
Directions
Take Minipress exactly as prescribed by your doctor. The dose should be slowly increased so that the blood pressure does not drop too fast.
The starting dose is 1 mg by mouth two or three times per day.
The maximum Minipress dosage is 20 mg by mouth two or three times per day. Your doctor will slowly increase the dose until you reach the blood pressure goal.
Ingredients
The active ingredient in Minipress is prazosin.
Interactions
Common drug-drug interactions include:
- ACE inhibitors
- Angotensin receptor blockers
- Loop diuretics
- Phosphodiesterase inhibitors
- Thiazide diuretics
Cautions
When you take Minipress for the first time, take it while sitting down and wait for 90 minutes because it can cause a fast drop in blood pressure. These effects subside after a few doses. The same effect may happen anytime the dosage is increased.
Do not drink alcohol way taking this medication.
Ask your doctor or pharmacist for a full list of precautions.
Side Effects
Side effects of Minipress may include:
- Blurred vision
- Constipation
- Depression
- Diarrhea
- Dizziness
- Drowsiness
- Dry mouth
- Dyspnea
- Edema
- Epistaxis
- Fatigue
- Headache
- Nasal congestion
- Nausea
- Nervousness
- Orthostatic hypotension
- Palpitations
- Skin rash
- Syncope
- Urinary frequency
- Vertigo
- Vomiting
- Weakness
References
- Minipress [package insert].New York, NY: Pfizer; 2009.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 1652