What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Norflex (Orphenadrine)


Norflex (Orphenadrine)

Prescription Required

100mg ER

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Generic Equivalent - Norflex (Orphenadrine)

Prescription Required


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  • Product Details


    Norflex (Orphenadrine) is a muscle relaxant used to alleviate stiffness, pain, and discomfort caused by strains, sprains, or other muscle injuries. The exact way it works is unknown. However, it can help relax the muscles in the body, especially when paired with rest, exercise, or therapy as part of a complete treatment plan. Orphenadrine is available as an extended-release tablet and injection.

    Fact Table




    US FDA, US DailyMed, EU EMA


    Fluticasone: 1%, Salmeterol: about 4%

    Legal status


    Chemical Name


    Elimination half-life

    13–20 hours

    Dosage (Strength)

    100mg, 100mg ER


    Consult Doctor - should be given to a pregnant woman only if clearly needed



    Protein binding


    PubChem CID






    ATC code






    Routes of administration



    The standard dosage for Norflex varies depending on specific needs and the severity of their condition. Follow the directions on the prescription label or as provided by a healthcare professional. Typically, the recommended dosage is one 100 mg tablet taken twice a day. The tablet should be swallowed whole, and it is crucial not to crush or chew it. It is important to maintain a consistent schedule when taking Orphenadrine, and the medication should be taken at the same time each day for maximum effectiveness.


    The primary ingredient in this medication is Orphenadrine Citrate.


    Avoid taking Norflex if any of the following conditions or circumstances apply:

    • Known or suspected allergy or hypersensitivity to Orphenadrine
    • Glaucoma
    • Pyloric or duodenal obstruction
    • Stenosing peptic ulcers
    • Prostatic hypertrophy or obstruction of the bladder neck
    • Cardio-spasm (megaesophagus)
    • Myasthenia gravis


    • When using Norflex (Orphenadrine), there are several cautions to keep in mind. Tell your healthcare provider about any of the following before starting treatment:
      • Any medications you currently take.
      • Other medical conditions you have.
      • Whether you are pregnant or breastfeeding.
    • Your ability to perform tasks that require alertness. Norflex may impair activities such as operating machinery or driving; exercise caution until you know how Norflex affects you.
    • Norflex contains ingredients that may cause allergic-type reactions, including anaphylactic symptoms and asthmatic episodes, particularly in sulfite-sensitive individuals. While general sulfite sensitivity is likely low, it is more common in asthmatic than non-asthmatic people.
    • Confusion, anxiety, and tremors have been reported in patients taking medications similar to Norflex. Dosage adjustments or discontinuation may be necessary if these symptoms occur.
    • Use Norflex with caution if you have tachycardia, cardiac decompensation, coronary insufficiency, cardiac arrhythmias, or other heart problems.
    • The safety of prolonged therapy with Norflex is not established. If long-term treatment is prescribed, periodic evaluations of your blood, urine, and liver function may be recommended.
    • Norflex falls under Pregnancy Category C, meaning there is no conclusive evidence from animal reproduction studies on its safety for pregnant women or the fetus. Therefore, Norflex should only be used during pregnancy if clearly needed and after careful consideration of the risks and benefits.

    Side Effects

    Norflex (Orphenadrine) may cause side effects in some people. Common side effects may include dizziness, drowsiness, weakness, nausea, vomiting, dry mouth, and constipation. These effects are generally mild and may not be severe enough to warrant stopping the medication.

    There are more serious side effects associated with Norflex that require immediate medical attention. Some of these may include hallucinations, tremor, and confusion. Signs or symptoms of an allergic reaction include hives, rash, swelling of the face or throat, and trouble breathing. If you or a loved one is taking Norflex and experiences any of these serious side effects, seek medical advice immediately.


    1. Norflex (Orphenadrine) Product Monograph. Northridge, CA: 3M Pharmaceuticals; 2006.
    2. Norflex (Orphenadrine) Drug Label Information. Bridgewater, NJ: Amneal Pharmaceuticals; 2019.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 11939

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