What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Noxafil Oral Suspension (Posaconazole)
Prescription Required
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Product Details
Description
Noxafil Oral Suspension (posaconazole) is a medication prescribed to prevent certain fungal infections in people who have a weak immune system. It's most often used in individuals who are at high risk of developing these infections, such as those undergoing stem cell transplants or chemotherapy.
Fact Table
Formula
C37H42F2N8O4
License
FDA approved
Bioavailability
Low (8 to 47% Oral)
Legal status
Rx-only
Chemical Name
Posaconazole
Elimination half-life
16 to 31 hours
Dosage (Strength)
105ml, 40mg / ml 105ml
Pregnancy
Consult Doctor
Brands
Noxafil Oral Suspension
Protein binding
98 to 99%
PubChem CID
147912
MedlinePlus
a607036
ChEBI
64355
ATC code
J02AC04
DrugBank
DB01263
KEGG
D02555
Routes of administration
Oral Suspension
Directions
Noxafil Oral Suspension is available in a 40 mg/mL concentration. The recommended noxafil oral suspension dosing for adults is 200 mg (5 mL) three times a day with meals. However, the dosage may vary depending on the condition being treated.
If you cannot eat a full meal, take Noxafil with a nutritional supplement or an acidic carbonated beverage. Always shake the bottle well before each use. Measure the dose with an oral syringe and swallow it directly without mixing it with any other liquid.
Noxafil is not approved for use in children under the age of 2.
Ingredients
The active ingredient in Noxafil Oral Suspension is posaconazole.
Contraindications
Share your allergy history with your healthcare provider. Do not take Noxafil Oral Suspension if you are allergic to posaconazole, other azole antifungal medicines, or any of the other ingredients in Noxafil.
Noxafil should not be taken with certain medications, including sirolimus, CYP3A4 substrates such as pimozide and quinidine, certain statin drugs, ergot alkaloids, and venetoclax. Noxafil oral suspension should be avoided in people with known or suspected hereditary fructose intolerance.
Cautions
- Before starting Noxafil, inform your doctor:
- About any other medications you are taking, including rifabutin, phenytoin, cimetidine, esomeprazole, digoxin, and fosamprenavir, among others.
- About any health conditions you have, including liver problems, kidney problems, electrolyte imbalances, and heart rhythm problems.
- If you are pregnant or plan to get pregnant. Noxafil could harm an unborn baby
- If you are breastfeeding or plan to breastfeed. Noxafil can pass into breast milk and may harm a breastfeeding child.
- Noxafil may cause changes in liver function. You may need to discontinue Noxafil if you develop abnormal liver tests.
- Noxafil may cause changes in your heart rhythm. If you experience palpitations or fainting spells, contact your doctor immediately.
- Noxafil may cause allergic reactions. Seek immediate medical attention if you develop skin rash, fever, swelling of the face, lips, tongue, or throat, difficulty breathing, or feeling faint.
Side Effects
The most common side effects of Noxafil Oral Suspension include fever, diarrhea, nausea, headache, vomiting, coughing, itching, and low potassium levels. If any of these persist or worsen, promptly inform your doctor.
With a valid prescription, you can buy Noxafil Oral Suspension online at a competitive price.
References:
Noxafil Prescribing Information. Kenilworth, NJ: Merck Sharp & Dohme Corp.; 2023.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12179
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