What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Orthovisc (Sodium Hyaluronate)


Orthovisc (Sodium Hyaluronate)

Prescription Required


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  • Product Details


    ORTHOVISC is an injectable medication prescribed to treat knee pain in people with osteoarthritis. It should only be used after trying nonpharmacologic therapies and simple analgesics like acetaminophen, ibuprofen, and naproxen.

    Osteoarthritis is a degenerative disease that affects the joints, including knees, hips, fingers, and shoulders. Over time, the cartilage and fluid in joints erode, making it more painful to move those joints. The ORTHOVISC injection can be directly injected into the knee to provide pain relief.

    Fact Table




    US FDA



    Legal status


    Chemical Name

    Sodium Hyaluronate

    Elimination half-life

    3 to 5 min

    Dosage (Strength)

    2ml Syringe





    Protein binding


    PubChem CID






    ATC code






    Routes of administration



    ORTHVISC injection should only be administered by a healthcare professional using an aseptic technique in a clinical, hospital, or another healthcare setting. ORTHVISC is injected once weekly for three weeks.


    ORTHOVISC injection is a single-use syringe that contains a solution of hyaluronan that is naturally-derived and dissolved in normal saline. Hyaluronan naturally occurs in the human body in joints and connective tissue and is used to lubricate these spaces. ORTHOVISC is prepared from chicken combs.


    Use caution if you have an allergy to avian feathers, eggs, or other chicken products.

    Do not administer ORTHOVISC injection into knee joints that are currently infected, inflamed, or afflicted with a skin disease.

    Store ORTHOVISC at room temperature and do not refrigerate or freeze the product. Do not use the product if the package seal has been broken.

    Side Effects

    Some of the most common adverse reactions from ORTHVISC may include:

    • Arthralgia
    • Back Pain
    • Edema at the injection site
    • Erythema at the injection site
    • Headache
    • Pain at the injection site

    For a full list of adverse reactions, speak with your physician performing the procedure.


    1. Orthovisc [package insert]. Woburn, MS 01801: Anika Therapeutics; 2001.
    2. WebMD, Basics of Osteoarthritis, Retrived April 2020

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 2430

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