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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
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Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Orthovisc (Sodium Hyaluronate)
Prescription Required
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Product Details
Description
ORTHOVISC is an injectable medication prescribed to treat knee pain in people with osteoarthritis. It should only be used after trying nonpharmacologic therapies and simple analgesics like acetaminophen, ibuprofen, and naproxen.
Osteoarthritis is a degenerative disease that affects the joints, including knees, hips, fingers, and shoulders. Over time, the cartilage and fluid in joints erode, making it more painful to move those joints. The ORTHOVISC injection can be directly injected into the knee to provide pain relief.
Fact Table
Formula
(C14H21NO11)n
License
US FDA
Bioavailability
-
Legal status
Rx-Only
Chemical Name
Sodium Hyaluronate
Elimination half-life
3 to 5 min
Dosage (Strength)
2ml Syringe
Pregnancy
Safe
Brands
Orthovisc
Protein binding
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PubChem CID
24759
MedlinePlus
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ChEBI
16336
ATC code
D03AX05
DrugBank
DB08818
KEGG
C00518
Routes of administration
injected
Directions
ORTHVISC injection should only be administered by a healthcare professional using an aseptic technique in a clinical, hospital, or another healthcare setting. ORTHVISC is injected once weekly for three weeks.
Ingredients
ORTHOVISC injection is a single-use syringe that contains a solution of hyaluronan that is naturally-derived and dissolved in normal saline. Hyaluronan naturally occurs in the human body in joints and connective tissue and is used to lubricate these spaces. ORTHOVISC is prepared from chicken combs.
Cautions
Use caution if you have an allergy to avian feathers, eggs, or other chicken products.
Do not administer ORTHOVISC injection into knee joints that are currently infected, inflamed, or afflicted with a skin disease.
Store ORTHOVISC at room temperature and do not refrigerate or freeze the product. Do not use the product if the package seal has been broken.
Side Effects
Some of the most common adverse reactions from ORTHVISC may include:
- Arthralgia
- Back Pain
- Edema at the injection site
- Erythema at the injection site
- Headache
- Pain at the injection site
For a full list of adverse reactions, speak with your physician performing the procedure.
References
- Orthovisc [package insert]. Woburn, MS 01801: Anika Therapeutics; 2001.
- WebMD, Basics of Osteoarthritis, Retrived April 2020
Frequently Asked Questions about Orthovisc (Sodium Hyaluronate)
What is Orthovisc (Sodium Hyaluronate)?
Orthovisc is a prescription medication that contains Sodium Hyaluronate. It is a viscosupplement injection used to relieve knee pain caused by osteoarthritis.
How does Orthovisc work to relieve knee pain?
Orthovisc is injected into the knee joint to provide lubrication and cushioning. Sodium Hyaluronate, the active ingredient, helps reduce friction in the joint and improve mobility, thereby relieving pain.
Who is a candidate for Orthovisc treatment?
Orthovisc is typically recommended for individuals with knee osteoarthritis who have not responded adequately to other conservative treatments such as pain medications or physical therapy. Your healthcare provider will assess your eligibility.
How is Orthovisc administered?
Orthovisc is administered as a series of injections directly into the knee joint by a healthcare professional. The number of injections and the frequency will be determined by your healthcare provider.
Are there any common side effects of Orthovisc?
Common side effects may include mild pain, swelling, warmth, or redness at the injection site. These side effects are usually temporary and resolve on their own.
Is Orthovisc a cure for knee osteoarthritis?
No, Orthovisc is not a cure for knee osteoarthritis. It provides temporary relief from pain and improves joint function. The effects are not permanent, and repeat treatments may be necessary.
Can I resume normal activities after receiving Orthovisc injections?
You should follow your healthcare provider's instructions regarding activity levels after Orthovisc injections. It's common to avoid strenuous activities immediately after the procedure.
Can pregnant or breastfeeding individuals receive Orthovisc injections?
The safety of Orthovisc during pregnancy and breastfeeding has not been established. If you are pregnant or breastfeeding, consult with your healthcare provider to discuss the potential risks and benefits.
How often are Orthovisc injections needed?
The frequency of Orthovisc injections can vary depending on your individual response and the severity of your knee osteoarthritis. Your healthcare provider will determine the appropriate treatment schedule.
Is Orthovisc suitable for all stages of knee osteoarthritis?
Orthovisc is typically recommended for individuals with mild to moderate knee osteoarthritis. It may not be as effective for advanced stages of the condition, and your healthcare provider will assess its suitability for your specific case.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 2430
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