Description 
         
Osurnia is a topical gel made for dogsā ears only and must never be used on cats. The drug contains an antibiotic, an antifungal, and a steroid, along with inactive ingredients that help the gel spread and stay in place. Itās used to treat outer ear infections (otitis externa) caused by common bacteria like Staphylococcus pseudintermedius and yeast such as Malassezia pachydermatis. It can help control infection, reduce swelling, and relieve discomfort.
 
        Directions
         
A veterinarian typically needs to administer Osurnia. Do not use this medication without veterinary supervision.
- The dog's ear canal will be cleaned and dried before applying the medication.
- Check that the eardrum (tympanic membrane) is intact.
- One dose (the entire tube) of Osurnia is squeezed into each infected ear.
- Application is repeated in 7 days.
After application, the base of the ear should be gently massaged to help the gel reach the lower ear canal. The dog should be restrained for a short time to minimize head shaking, which can cause the medication to splatter. Do not clean the ear canal for 45 days after the first treatment. Cleaning sooner may decrease how well the medicine works.
 
        Ingredients
         
Osurnia contains the active ingredients terbinafine, florfenicol, and betamethasone acetate.
Contraindications
Avoid giving this medication if any of the following apply:
- Known or suspected perforation of the ear drum
- Allergy or hypersensitivity to florfenicol, terbinafine, or corticosteroids
Cautions
         
- Before giving this medication, you may want to consult a veterinarian about the following:
- Any existing health conditions
- Any allergies
- A list of all medications currently being taken
- Osurnia is for use in dogs only. Keep it out of reach of children, and seek medical help if itās accidentally swallowed. If it gets in your eyes, rinse with water for at least 15 minutes and see a doctor if irritation develops. Wash the skin thoroughly with water if contact occurs.
- When applying Osurnia, wear eye protection and hold your dogās head steady to reduce splatter and prevent accidental eye injury to you or your dog. This is especially important because the product can irritate or damage the eyes.
- Your veterinarian should check your dogās eardrum before each dose, as Osurnia has not been tested in dogs with a ruptured eardrum. If your dog shows signs like hearing loss, head tilt, balance problems, unusual eye movements, or facial drooping during treatment, contact a vet immediately.
- Do not give Osurnia by mouth. In some cases, the use of ear medications with steroids can affect hormone levels in dogs. It should also be used carefully in dogs with liver problems.
- The safety of Osurnia in breeding dogs, pregnant dogs, or nursing mothers has not been established. Your vet will help decide if the benefits outweigh the risks in these situations.
Side Effects
         
The most common side effects reported with Osurnia during clinical studies were elevated liver enzymes, vomiting, and, in rare cases, hearing loss. Less common effects included weight loss or a decrease in hearing, which occurred in both treated and placebo groups. Post-approval reports have also observed deafness, ear discharge, ear pain, head shaking, balance problems, and neurological signs such as facial paralysis.
Accidental human exposure, especially if the dog shakes its head after treatment, can cause eye irritation or corneal ulcers. In dogs, additional side effects reported include poor muscle control, eye injury, and ruptured eardrum. Watch your pet closely after application and seek veterinary advice if any unusual signs appear.
References:
- Osurnia Drug Label Information. Overland Park, KS: Dechra Veterinary Products; 2024.
- Osurnia Package Insert. Overland Park, KS: Dechra Veterinary Products; 2022.
       About Dr. Gerardo Sison (Page Author)
          
Dr. Sison graduated with honors from the University of Florida. He began his career in pharmacy counseling patients in a community setting and later served in hospitals and clinics. He has also worked in medication therapy management services. Read More....
 
 
 
    
    IMPORTANT NOTE:
    The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
    Product Code : 15291