What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Prevymis (Letermovir)
Prescription Required
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Product Details
Description
Prevymis (Letermovir) is an antiviral drug classified as a cytomegalovirus (CMV) DNA terminase complex inhibitor. It blocks the viral DNA from replicating, helping to prevent infection. Doctors generally prescribe Prevymis to prevent CMV infection in patients who have received an allogeneic hematopoietic stem cell (bone marrow) transplant and are at high risk for CMV.
Directions
The standard dosage of Prevymis is 480 mg, taken once daily, either orally or intravenously. When taking with cyclosporine, the dose should be adjusted to 240 mg. If taking Prevymis orally, patients should swallow the tablet whole without crushing, chewing, or breaking it. They can take the medication with or without food. If received intravenously, the dose is administered over one hour each day. Avoid any dosage adjustments without consulting a healthcare provider.
Ingredients
The active ingredient in Prevymis is Letermovir.
Contraindications
Avoid taking or using this medication if any of the following apply:
- You are allergic to Letermovir or any ingredients in the medication.
- You have severe liver impairment (Child-Pugh Class C).
- You are taking certain drugs that interact negatively with Letermovir, such as pimozide, ergot alkaloids, and pitavastatin or simvastatin (when co-administered with cyclosporine).
Cautions
- Before starting treatment with Prevymis, be sure to inform your healthcare provider about the following:
- Any medical conditions you currently have
- Any allergies
- All medications you are currently taking
- Whether you are pregnant or breastfeeding
- Be aware of potential drug interactions. Combining Prevymis with certain medications could cause significant interactions, possibly leading to unwanted side effects or reduced effectiveness of the treatments.
- Always check for interactions with a healthcare provider before starting new medications while on Prevymis and monitor for any unexpected or adverse reactions.
Side Effects
Prevymis commonly causes nausea, vomiting, diarrhea, cough, headache, tiredness, stomach pain, and swelling in the arms or legs. The side effects reported with Prevymis are typically mild to moderate in severity. Although heart-related side effects are more common with Prevymis, they can generally be managed under medical supervision. If you experience any concerning symptoms, it is crucial to consult your healthcare provider immediately.
References
- Prevymis (Letermovir) Product Monograph. Rahway, NJ: Merck Sharp & Dohme LLC; 2023.
- Prevymis (Letermovir) Drug Label Information. Rahway, NJ: Merck Sharp & Dohme LLC; 2023.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14602
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