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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Propalin (Phenylpropanolamine HCl)

Brand

Propalin (Phenylpropanolamine HCl)

Prescription Required

Strength
Qty
50mg / ml Syrup

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  • Product Details

    Description

    Propalin contains a medicine called phenylpropanolamine hydrochloride and is given by mouth to dogs. Veterinarians mainly use it to manage urinary incontinence in dogs that have weak muscles around the urethra, especially in female dogs that were spayed. The medicine works by tightening the muscles in the urethra, which helps stop unwanted leaking of urine.

    Directions

    Propalin is given by mouth with the provided oral syringe. Shake the bottle before use and measure the dose carefully to match the dog's correct weight. To avoid overdose, always weigh the dog and confirm the dose each time. The recommended dosage is 1 mg per kg of bodyweight. This equals 0.1 ml of syrup for every 5 kg of bodyweight, three times per day. Giving the medicine mixed in food is common, but it can also be given directly into the mouth.

    Ingredients

    Phenylpropanolamine is the active ingredient in Propalin.

    Contraindications

    Avoid giving this medication in which the following apply:

    • Dogs with behavioral issues causing inappropriate urination
    • Dogs taking non-selective monoamine oxidase inhibitors (MAOIs)
    • Dogs that have a known hypersensitivity or allergy to phenylpropanolamine or any of its ingredients

    Cautions

    • Before giving this medication, you may want to consult a veterinarian about the following:
      • Any existing health conditions
      • Any allergies
      • A list of all medications currently being taken
    • Propalin must be given at the exact dose prescribed by your vet, based on your dog’s weight. Giving too much can cause overdose, so always measure it carefully.
    • This medication can affect blood pressure and heart rate, so it should be used carefully in dogs with heart problems. Extra caution is also needed for dogs with kidney or liver disease, diabetes, glaucoma, overactive thyroid, Cushing’s disease, or other metabolic problems.
    • For young female dogs under 1 year old, your vet may check for structural causes of incontinence before starting treatment.
    • Propalin contains phenylpropanolamine, which can be toxic if swallowed by people, especially children. Always store it securely and replace the cap tightly after use.
    • If it’s accidentally swallowed by a person, seek immediate medical help and show the doctor the package. Overdose symptoms may include dizziness, headache, nausea, trouble sleeping, restlessness, or high blood pressure.
    • If the product gets on your skin, wash with soap and water. If it gets in your eyes, rinse with clean water for 15 minutes and get medical advice. Always wash your hands after giving the medication.
    • Do not give Propalin to pregnant or nursing dogs.
    • Tell your vet about any other medications your dog is taking, especially certain antidepressants, MAOIs, or other drugs that affect the nervous system, as some combinations can be dangerous.
    • Dispose of unused medication safely, and never pour it down the drain. Ask your vet or pharmacist how to throw it away in a way that protects the environment.

    Side Effects

    Side effects with Propalin are rare but can occur. In some dogs, it may cause increased heart rate, higher blood pressure, or protein in the urine. Other possible signs include dizziness, decreased appetite, irregular heartbeat, aggression, hyperactivity, increased thirst or urination, incoordination, seizures, or allergic reactions.

    Less commonly, dogs may develop loose stools, vomiting, or lethargy. Most side effects come from the body’s “fight-or-flight” response and can be mild or serious. If your dog shows any unexpected changes, even ones not listed here, stop the medication and call your veterinarian.

    References:

    1. Propalin syrup Labelling and Package Leaflet. Lure, France: Vetoquinol S.A; 2025.
    2. Propalin syrup Summary of Product Characteristics. Lure, France: Vetoquinol S.A; 2025.


    Dr Gerardo Sison
    About Dr. Gerardo Sison (Page Author)


    Dr. Sison graduated with honors from the University of Florida. He began his career in pharmacy counseling patients in a community setting and later served in hospitals and clinics. He has also worked in medication therapy management services. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 15294

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