What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Aceon (Perindopril)
Also Known as Coversyl
Prescription Required
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Product Details
Description
Aceon (perindopril erbumine), an angiotensin-converting enzyme inhibitor (ACE-I) is used to treat high blood pressure and stable coronary artery disease (CAD) to decrease the risk of cardiovascular death or heart attack.
Aceon comes in oral tablets of 2 mg, 4 mg, and 8 mg strengths.
Fact Table
Formula
C19H32N2O5
License
US FDA
Bioavailability
24%
Legal status
Rx-Only
Chemical Name
Perindopril
Elimination half-life
1–17 hours
Dosage (Strength)
2mg, 4mg, 8mg
Pregnancy
Not recommended
Brands
Aceon
Protein binding
20%
PubChem CID
107807
MedlinePlus
a602017
ChEBI
8024
ATC code
C09AA04
DrugBank
DB00790
KEGG
D03753
Routes of administration
By mouth
Directions
Read all the information that comes with your prescription. Take Aceon as your doctor has prescribed. Talk to your doctor or pharmacist about any questions or concerns that arise.
The recommended starting dose for treating high blood pressure is 4 mg by mouth once daily. Your doctor may increase the dose, up to a maximum of 16 mg per day, until your blood pressure is controlled.
The recommended starting dose for treating stable CAD is 4 mg by mouth once daily for two weeks, then increased, as tolerated, to a maintenance dose of 8 mg by mouth once daily.
Ingredients
Each tablet of Aceon contains perindopril erbumine and the following inactive ingredients: colloidal silica (hydrophobic), lactose, magnesium stearate, and microcrystalline cellulose. Iron oxide is also found in the 4 mg and 8 mg tablets.
Contraindications
Do not take Aceon if you've had angioedema (swelling underneath the skin) with previous ACE-I use or if you have hereditary or idiopathic angioedema.
Cautions
Aceon has a FDA Boxed Warning against the use of the medication during pregnancy as it can harm or cause death to a developing fetus.
- Before you start taking Aceon, tell your doctor:
- About all the prescription and over-the-counter medications you take, as Aceon can interact with certain medications, including potassium supplements, potassium-sparing diuretics, lithium, and nonsteroidal anti-inflammatory drugs (NSAIDs)
- About your allergies
- About your medical history and health conditions
- If you are pregnant or breastfeeding
- Aceon can cause kidney problems.
- Aceon can cause symptomatic low blood pressure. Blood pressure should be monitored regularly.
- Aceon can cause high potassium levels.
- Aceon can cause abnormal white blood cell counts and bone marrow depression. This occurs more often in patients with kidney problems, lupus, or scleroderma.
- Aceon can cause a nonproductive cough.
- Although rare, Aceon can cause liver problems. Seek medical attention immediately if you develop yellowing of the skin or whites of the eyes.
- Aceon can cause head, neck, and intestinal angioedema.
- Aceon can cause a dry cough.
Side Effects
The most common Aceon side effects include cough, dizziness, back pain, and low blood pressure. However, you should contact your doctor immediately if you have side effects that bother you or won't go away.
Reference:
- Aceon (perindopril erbumine). Berkeley, CA: XOMA (US) LLC; 2012.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1312
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