What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Climara Patch (Estradiol)
Also Known as Climara Forte
Prescription Required
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Product Details
Description
What is estradiol and estradiol levels?
Chemical Name: ESTRADIOL (ess-tra-DYE-ole)Climara Patch (Estradiol)
Climara patch is a female hormone transdermal application containing estrogen in the form of estradiol. Basically, estrogen is produced by the female ovaries. It performs a vital function in the female body, but after menopause, as its levels dwindle away, uncomfortable symptoms like hot flashes, vaginal dryness, burning, and irritation may develop. Estradiol patch is used to reduce these menopausal symptoms.
In addition to this, Climara patch is also used to prevent postmenopausal osteoporosis which can severely affect the musculoskeletal system. Furthermore, it is also used in the treatment of ovarian disorders.
On the prescription of your physician, you can easily buy Climara patch. Furthermore, you can buy Estradiol patch from Canada Pharmacy and have it be directly delivered to you.
Directions
Put the patch, sticky side down, on clean, dry skin that is not oily, red, irritated, or broken. For Climara, place it on the lower belly below the navel or the upper buttocks. For Climara Pro, place it on the lower belly. Do not put it on the breasts or where tight clothing may rub it off.
Press the patch firmly for about 10 seconds, making sure the edges stick. Replace it once a week, using a different spot each time and waiting at least 1 week before using the same area again. Apply the patch right after opening the pouch, and do not store it outside the pouch.
Climara usually starts at the lowest dose, and your healthcare provider may adjust it based on how you respond. The goal is to use the lowest dose that works for the shortest time needed, with checkups every 3 to 6 months. If you still have a uterus and use Climara, you may also need a progestin to help lower the risk of uterine lining cancer. Climara Pro already contains a progestin.
Ingredients
The active ingredient in Climara is estradiol, while Climara Pro contains estradiol and the progestin levonorgestrel. The patches may also contain inactive ingredients, including an acrylate copolymer adhesive, fatty acid esters, and a polyethylene backing film.
Cautions
Before using this medication, you may want to consult a healthcare provider about the following:
- Any existing health conditions
- Any allergies
- A list of all medications currently being taken
Estrogens, with or without a progestin, can increase the risk of serious conditions, including cancer of the uterine lining, also called endometrial cancer; breast cancer; blood clots; stroke; and heart attack. In women 65 and older, there may be an increased risk of dementia.
Estrogens can increase the risk of gallbladder disease and raise blood pressure or triglyceride levels. Tell your healthcare provider if you have or have had gallbladder problems, high blood pressure, high triglycerides, an underactive thyroid, migraines, asthma, epilepsy, diabetes, lupus, or conditions that can be worsened by fluid retention, such as heart or kidney problems.
Stop the medication and contact your healthcare provider if you develop severe high blood calcium, very high triglycerides, yellowing of the skin or eyes, which may be a sign of liver problems, or sudden vision loss or other eye problems.
Certain medications that affect liver enzymes, or CYP3A4, such as some seizure medicines, rifampin, and St. John’s wort, can change how much estrogen is in your body. Tell your healthcare provider about all the medicines and supplements you take.
Apply the patch only to the recommended areas of skin, and never to the breasts. Choose skin that is clean and dry to help it stick to the skin. Climara and Climara Pro must not be used during pregnancy.
Store at room temperature, 20°C to 25°C (68°F to 77°F), and do not store above 30°C (86°F) or unpouched.
Used patches still contain hormones. Fold the sticky sides together, place it in a child-proof container, and throw it in the trash. Do not flush it. Keep it out of reach of children.
Contraindications
Avoid taking or using this medication if any of the following apply:
- Unusual vaginal bleeding that has not been diagnosed.
- A current or past history of breast cancer, or any cancer that is known or suspected to be sensitive to estrogen.
- A current or past blood clot in the legs or lungs, also called deep vein thrombosis or pulmonary embolism.
- A clotting disorder, such as protein C, protein S, or antithrombin deficiency.
- A current or past stroke or heart attack, also called arterial clot-related disease.
- Liver problems, such as liver disease.
- A known allergic reaction, including anaphylaxis or angioedema, or hypersensitivity to Climara or Climara Pro.
- Known or suspected pregnancy.
Side Effects
Common side effects of Climara include:
- Breast pain or tenderness
- Headache
- Upper respiratory tract infection, or cold-like symptoms
- Abdominal, or stomach, pain
- Generalized pain
- Swelling from fluid retention, also called edema
- Redness or irritation of the skin where the patch is applied
With Climara Pro, vaginal bleeding or spotting, back pain, depression, and flu-like symptoms have also been reported. Stop using the patch and get medical help if you have signs of a serious problem, such as chest pain, sudden shortness of breath, coughing up blood, pain or swelling in a leg, sudden severe headache, vision or speech changes, or weakness or numbness on one side of the body, which can be signs of a blood clot, stroke, or heart attack. Also, seek medical care for signs of a serious allergic reaction, such as swelling of the face or throat, trouble breathing, or hives; a new breast lump; unusual or heavy vaginal bleeding; or signs of liver and gallbladder problems, such as yellowing of the skin or eyes. Contact your healthcare provider if skin irritation at the patch area is severe or does not go away.
References
Climara, estradiol transdermal system, Prescribing Information. Whippany, NJ: Bayer HealthCare Pharmaceuticals Inc.; 2026.
Climara Pro, estradiol/levonorgestrel transdermal system, Prescribing Information. Whippany, NJ: Bayer HealthCare Pharmaceuticals Inc.; 2026.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1415
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