Cuprimine (Penicillamine) 

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Cuprimine (Penicillamine) 

(Also known as Distamine, Depen)
Manufactured by: Merck Frosst

Prescription Required

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Generic Equivalent

to (Cuprimine (Penicillamine) )
Generic equivalents are not manufactured by: Merck Frosst

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Cuprimine Drug Information

Buy Cuprimine Online (Penicillamine) 250 mg Chemical Name: PENICILLAMINE (pen-i-SILL-a-meen)

Cuprimine (Penicillamine)

Cuprimine is a chelating agent. It is used in the treatment of rheumatoid arthritis, Wilson’s disease (high levels of copper in the body causing damage to liver, brain and other organs) and cystinuria which causes the formation of kidney stones.

For treating rheumatoid arthritis, penicillamine is known as DMARD (disease modifying anti-rheumatic drug). It reduces pain, tenderness, and swelling in the joints. But Cuprimine is not used to treat juvenile rheumatoid arthritis.

For treating Wilson’s disease, penicillamine binds with excess copper and removes it from the body. Decreasing the levels of copper improves liver function and mental, mood or nerve problems manifested as confusion, difficulty in walking, and speaking.

For treating cystinuria, penicillamine reduces the levels of amino acid, cysteine in urine thus lowering the chances of developing kidney stones.

Cuprimine is easily available, and you can go ahead and buy Cuprimine online from Canada Pharmacy.


The active ingredient (comes in 2 strengths):

  • Penicillamine 125 mg
  • Penicillamine 250 mg


Cuprimine dosage should be strictly followed as prescribed by your doctor. Usually, Cuprimine is taken on an empty stomach, at least 1 hour before or 2 hours after a meal. Do not drink milk or take antacids or food 1 hour before or 1 hour after you take Cuprimine. Furthermore, take large quantities of fluid with Cuprimine. It may take 2 to 3 months before you might start seeing any improvement in the prescribed condition.

Your doctor might also add multivitamins or extra iron or vitamin B6 with Cuprimine intake. Only take the supplements advised by your doctor.


Before taking Cuprimine, consult your doctor if you have:

  • Liver disease
  • Allergy to penicillin
  • Stomach ulcers
  • Weak immune system
  • Malnourished
  • Pregnancy
  • Breastfeeding
  • Using gold injections

Side Effects:

 In case of adverse effects, immediately consult your doctor. Side effects associated with Cuprimine are as follows:

  • Sudden fever
  • Skin rash
  • Joint pain
  • Swollen glands
  • Easy bruising or bleeding
  • Sudden weakness
  • Sore throat
  • Mouth or skin sores, red or swollen gums
  • Swelling of hands, legs, or feet
  • Pain or burning when urinating, foamy or bloody urine, lower backache
  • Lightheadedness, shortness of breath
  • Muscle weakness in the face, double vision, drooping eyelids
  • Nausea, vomiting, stomach pain, loss of appetite
  • Ringing in ears
  • Inability of the wound to heal

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

Product Code: 1442
Product Reviews

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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