Diabeta (Glyburide)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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Prescription Required

  • Product Details


    What is Diabeta?

    How does it work?

    • It works by increasing the amount of insulin released by your pancreas.

    How should I store it?

    • Store your Diabeta at room temperature and keep it out of reach of children.

    Fact Table




    AU, US FDA



    Legal status

    RX Only

    Chemical Name


    Elimination half-life

    10 hours

    Dosage (Strength)

    1.25mg, 2.5mg, 5mg


    No risk in other studies


    Diabeta, Glucovance, Glynase

    Protein binding


    PubChem CID






    ATC code






    Routes of administration

    By mouth


    Should I take Diabeta with food?

    • Take your Diabeta with your first meal of the day.

    Are there any special instructions?

    • Take your Diabeta exactly as prescribed by your doctor.

    What is the usual Diabeta dosage?

    • Take 5mg by mouth once daily.
      • Your doctor could adjust your dose to meet your needs.


    What is the active ingredient in Diabeta?

    • Glyburide

    What are the inactive ingredients?

    • For a complete list of inactive ingredients, click here or check the product packaging.


    Diabeta could interact with the following medications:

    • NSAID drugs
    • ACE inhibitors
    • Disopyramide
    • Fluoxetine
    • Clarithromycin
    • Salicylates
    • Sulfonamides
    • Chloramphenicol
    • Probenecid
    • MAOI drugs
    • Beta adrenergic blockers
    • Bosentan
    • Miconazole
    • Fluoroquinolone antibiotics
    • Coumarin derivatives
    • Rifampin
    • Thiazide diuretics
    • Corticosteroids
    • Phenothiazines
    • Oral estrogens
    • Phenytoin
    • Nicotinic acid
    • Sympathomimetics
    • Calcium channel blockers
    • Isoniazid
    • Cyclosporine
    • Colesevelam



    Who should avoid taking Diabeta?

    • Do not use Diabeta if you have a known allergy to any of the ingredients.
    • Do not take Diabeta if you have any of the following conditions:
      • Type 1 diabetes
      • Diabetic ketoacidosis
    • Do not use Diabeta with Bosentan.

    What are the risks?

    • If you are pregnant, breastfeeding, or considering becoming pregnant, talk to your doctor about the risks of using Diabeta.
    • Using oral hypoglycemic drugs has been reported to be associated with an increased rate of death due to cardiovascular problems.
    • If you are allergic to sulfonamide drugs, you could also be allergic to glyburide. Talk to your doctor about your risk.
    • Diabeta can cause severe hypoglycemia. Talk to your doctor about your risk.
    • If you have G6PD, you could develop hemolytic anemia while using Diabeta.

    Side Effects

    What are the potential side effects of Diabeta?

    • Hypoglycemia
    • Cholestatic jaundice
    • Hepatitis
    • Liver enzyme abnormalities
    • Nausea
    • Epigastric fullness
    • Heartburn
    • Allergic skin reactions
    • Pruritis
    • Erythema
    • Urticaria
    • Maculopapular eruptions
    • Erythema multiforme
    • Exfoliative dermatitis
    • Porphyria cutanea tarda
    • Photosensitivity
    • Leukopenia
    • Agranulocytosis
    • Thrombocytopenia
    • Hemolytic anemia
    • Aplastic anemia
    • Pancytopenia
    • Disulfiram-like reactions
    • SIADH
    • Blurred vision
    • Angioedema
    • Arthralgia
    • Myalgia
    • Vasculitis


    Other Considerations

    • Compare Canada Pharmacy's Diabeta price to your local pharmacy.


    1. DailyMed - glyburide tablet. (2019). Retrieved May 24, 2020.
    2. WebMD: What Is Insulin?. (2019). Retrieved: July 23, 2020.

    Frequently Asked Questions about Diabeta (Glyburide)

    What is Diabeta (Glyburide)?

    Diabeta (Glyburide) is an oral antidiabetic medication used to treat type 2 diabetes. It belongs to a class of drugs known as sulfonylureas.

    How does Diabeta work?

    Diabeta works by stimulating the pancreas to release more insulin, which helps lower blood sugar levels.

    How should I take Diabeta?

    Always take Diabeta as prescribed by your doctor. It is usually taken once or twice a day with meals.

    What are the possible side effects of Diabeta?

    Common side effects include nausea, heartburn, weight gain, and headache. Severe side effects may include low blood sugar (hypoglycemia), allergic reactions, and liver problems.

    Can I drink alcohol while taking Diabeta?

    Alcohol can increase the risk of low blood sugar. It's best to discuss with your doctor about alcohol consumption while on Diabeta.

    What should I do if I miss a dose?

    If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

    Can I take Diabeta during pregnancy?

    Diabeta may not be safe during pregnancy. Always consult with your doctor if you are pregnant or planning to become pregnant while on this medication.

    Are there any drug interactions with Diabeta?

    Yes, Diabeta can interact with other medications. Always inform your doctor about all the medications, supplements, and herbal products you are taking.

    How should I store Diabeta?

    Store Diabeta at room temperature, away from moisture and heat. Keep it out of reach of children.

    Can Diabeta be used in combination with other diabetes medications?

    Yes, Diabeta can be used in combination with other diabetes medications. However, always consult with your doctor before making any changes to your medication regimen.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1465

  • Product Reviews


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