Diabeta (Glyburide)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    What is Diabeta?

    How does it work?

    • It works by increasing the amount of insulin released by your pancreas.

    How is it supplied?

    • You can buy Diabeta online at Canada Pharmacy as 5mg tablets in bottles of 100.

    How should I store it?

    • Store your Diabeta at room temperature and keep it out of reach of children.

    Fact Table

    Formula

    C23H28ClN3O5S

    License

    AU, US FDA

    Bioavailability

    -

    Legal status

    RX Only

    Chemical Name

    Glyburide

    Elimination half-life

    10 hours

    Dosage (Strength)

    1.25mg, 2.5mg, 5mg

    Pregnancy

    No risk in other studies

    Brands

    Diabeta, Glucovance, Glynase

    Protein binding

    99.9%

    PubChem CID

    3488

    MedlinePlus

    a684058

    ChEBI

    5441

    ATC code

    A10BB01

    DrugBank

    DB01016

    KEGG

    D00336

    Routes of administration

    By mouth

    Directions

    Should I take Diabeta with food?

    • Take your Diabeta with your first meal of the day.

    Are there any special instructions?

    • Take your Diabeta exactly as prescribed by your doctor.

    What is the usual Diabeta dosage?

    • Take 5mg by mouth once daily.
      • Your doctor could adjust your dose to meet your needs.

    Ingredients

    What is the active ingredient in Diabeta?

    • Glyburide

    What are the inactive ingredients?

    • For a complete list of inactive ingredients, click here or check the product packaging.

    Interactions

    Diabeta could interact with the following medications:

    • NSAID drugs
    • ACE inhibitors
    • Disopyramide
    • Fluoxetine
    • Clarithromycin
    • Salicylates
    • Sulfonamides
    • Chloramphenicol
    • Probenecid
    • MAOI drugs
    • Beta adrenergic blockers
    • Bosentan
    • Miconazole
    • Fluoroquinolone antibiotics
    • Coumarin derivatives
    • Rifampin
    • Thiazide diuretics
    • Corticosteroids
    • Phenothiazines
    • Oral estrogens
    • Phenytoin
    • Nicotinic acid
    • Sympathomimetics
    • Calcium channel blockers
    • Isoniazid
    • Cyclosporine
    • Colesevelam

     

    Cautions

    Who should avoid taking Diabeta?

    • Do not use Diabeta if you have a known allergy to any of the ingredients.
    • Do not take Diabeta if you have any of the following conditions:
      • Type 1 diabetes
      • Diabetic ketoacidosis
    • Do not use Diabeta with Bosentan.

    What are the risks?

    • If you are pregnant, breastfeeding, or considering becoming pregnant, talk to your doctor about the risks of using Diabeta.
    • Using oral hypoglycemic drugs has been reported to be associated with an increased rate of death due to cardiovascular problems.
    • If you are allergic to sulfonamide drugs, you could also be allergic to glyburide. Talk to your doctor about your risk.
    • Diabeta can cause severe hypoglycemia. Talk to your doctor about your risk.
    • If you have G6PD, you could develop hemolytic anemia while using Diabeta.

    Side Effects

    What are the potential side effects of Diabeta?

    • Hypoglycemia
    • Cholestatic jaundice
    • Hepatitis
    • Liver enzyme abnormalities
    • Nausea
    • Epigastric fullness
    • Heartburn
    • Allergic skin reactions
    • Pruritis
    • Erythema
    • Urticaria
    • Maculopapular eruptions
    • Erythema multiforme
    • Exfoliative dermatitis
    • Porphyria cutanea tarda
    • Photosensitivity
    • Leukopenia
    • Agranulocytosis
    • Thrombocytopenia
    • Hemolytic anemia
    • Aplastic anemia
    • Pancytopenia
    • Disulfiram-like reactions
    • SIADH
    • Blurred vision
    • Angioedema
    • Arthralgia
    • Myalgia
    • Vasculitis

     

    Other Considerations

    • Compare Canada Pharmacy's Diabeta price to your local pharmacy.

    References:

    1. DailyMed - glyburide tablet. (2019). Retrieved May 24, 2020.
    2. WebMD: What Is Insulin?. (2019). Retrieved: July 23, 2020.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1465

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