What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Lipofen (Fenofibrate Micro) (NOT = Tricor)
Also Known as Lipidil Micro
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Generic Equivalent - Lipofen (Fenofibrate Micro) (NOT = Tricor)
Prescription Required
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Product Details
Description
Lipofen is a prescription drug that your doctor might give you to treat high cholesterol. It is usually used to treat a specific type of cholesterol called triglycerides. High triglycerides are a major risk factor for pancreatitis and heart disease.
Lipofen works by attaching to the nuclear transcription factor peroxisome proliferator-activated receptor-alpha (PPAR-alpha). Attaching to this transcription factor prevents the formation of certain types of cholesterol. Since Lipofen has not been linked to a reduction in fatal heart disease, it should not be given as the only treatment for high cholesterol.
Fact Table
Formula
C20H21ClO4
License
US FDA, EU EMA
Bioavailability
-
Legal status
Rx-only
Chemical Name
Fenofibrate
Elimination half-life
20h
Dosage (Strength)
50mg, 134mg, 150mg, 200mg
Pregnancy
No Known Risk
Brands
Fenoglide, Lipofen
Protein binding
99%
PubChem CID
3339
MedlinePlus
a601052
ChEBI
5001
ATC code
C10AB05
DrugBank
DB01039
KEGG
D00565
Routes of administration
By mouth
Directions
Take 50-150 mg by mouth once daily as directed by your doctor. Lipofen should be taken with food.
Ingredients
The active ingredient in Lipofen is fenofibrate.
Interactions
The most common drug-drug interactions with this drug include:
- Acipimox
- Bile Acid Sequestrants
- Ciprofibrate
- Colchicine
- CycloSPORINE
- Ezetimibe
- Fosphenytoin-Phenytoin
- HMG-CoA Reductase Inhibitors
- Raltegravir
- Sulfonylureas
- Tacrolimus
- Vitamin K Antagonists
- Warfarin
Cautions
Tell your doctor if you have a history of kidney or liver problems before starting this drug.
Tell your doctor if you have a history of blood clots before starting this medication.
Use caution if you are also taking statin medications for the treatment of cholesterol because it can increase the risk of muscle disease.
Side Effects
Common side effects of this medication may include:
- Abdominal pain
- Acute generalized exanthematous pustulosis
- Acute kidney injury
- Agranulocytosis
- Anaphylaxis
- Anemia
- Angioedema
- Arthralgia
- Asthenia
- Cholestatic hepatitis
- Constipation
- Decreased HDL cholesterol
- Diarrhea
- Dizziness
- Dyspepsia
- Headache
- Hepatic cirrhosis
- Hepatitis
- Hepatotoxicity
- Increased creatine phosphokinase
- Increased serum alanine aminotransferase
- Increased serum aspartate aminotransferase
- Increased serum bilirubin
- Increased serum creatinine
- Interstitial pulmonary disease
- Limb pain
- Muscle spasm
- Myalgia
- Myopathy
- Nasopharyngitis
- Pain
- Pancreatitis
- Pulmonary embolism
- Rhabdomyolysis
- Rhinitis
- Sinusitis
- Skin photosensitivity
- Skin rash
- Stevens-Johnson syndrome
- Thrombocytopenia
- Toxic epidermal necrolysis
- Upper respiratory tract infection
- Urticaria
References
Lipofen [package insert]. Juncos, Puerto Rico: Galephar Pharmaceutical Research Inc.; 2006.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1523
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