What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Lidex Cream (Fluocinonide) (Lyderm in Canada)


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Generic Equivalent - Lidex Cream (Fluocinonide) (Lyderm in Canada)

Prescription Required

0.05% 25g

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  • Product Details


    LIDEX cream (fluocinonide) is a topical medication that can be prescribed to treat skin conditions. LIDEX is commonly prescribed to treat conditions like eczema and psoriasis but can be used for any inflammatory and pruritic dermatologic condition.

    LIDEX cream contains the corticosteroid fluocinonide. Corticosteroids work by suppressive the immune system where they are applied. They can relieve swelling, itching, inflammation, and pain. Corticosteroids accomplish this by blocking the formation of the chemical precursor arachidonic acid.


    Wash hands thoroughly before and after application.

    The normal LIDEX cream dosage is to apply a thin layer to the affected area two to four times daily. 

    Do not use LIDEX cream for longer than two weeks in a row unless directed by your doctor.


    The active ingredient in LIDEX is fluocinonide.

    The other (inactive) ingredients in LIDEX cream include:

    • 1,2,6-hexanetriol
    • Cetyl alcohol
    • Citric acid monohydrate
    • Mineral oil
    • Propylene glycol
    • Stearyl alcohol

    Fact Table







    Legal status

    RX Only

    Chemical Name


    Elimination half-life


    Dosage (Strength)

    0.05% (60 grams)


    Consult a doctor


    Lidemol, Lidex, Lyderm, Tiamol, Vanos

    Protein binding


    PubChem CID






    ATC code

    C05AA11, D07AC08





    Routes of administration



    Do not use fluocinonide with aldesleukin. 

    LIDEX has very few known drug-drug interactions.


    Skin infections way develop while taking corticosteroid therapy. Tell your doctor if your skin worsens or the appearance changes while using LIDEX.

    Topical steroids may be absorbed into the bloodstream, especially if used on open wounds. Use caution if you have a history of hyperglycemia, glycosuria, or Cushing syndrome.

    Do not wrap occlusive dressing over topical steroids and do not use them for an extended period (greater than 2 weeks at a time).

    Side Effects

    The most common adverse effects from LIDEX cream include:

    • Acneiform eruptions
    • Allergic contact dermatitis
    • Burning
    • Dryness
    • Folliculitis
    • Hypertrichosis
    • Hypopigmentation
    • Irritation
    • Itching
    • Maceration of the skin
    • Miliaria
    • Perioral dermatitis
    • Secondary infection
    • Skin Atrophy
    • Striae


    Lidex [package insert]. North Wales, PA: Teva; 2016.

    Frequently Asked Questions about Lidex Cream/Lyderm

    What is Lidex Cream/Lyderm?

    Lidex Cream, also known as Lyderm in Canada, is a topical corticosteroid medication containing fluocinonide. It is used to treat a variety of skin conditions, such as eczema, dermatitis, allergies, and rash.

    How does Lidex Cream/Lyderm work?

    It works by reducing inflammation, itching, and redness on the skin. Fluocinonide is a potent corticosteroid that suppresses the immune response in the skin, leading to decreased inflammation.

    How should I use Lidex Cream/Lyderm?

    Apply a thin layer of the cream to the affected area(s) as prescribed by your healthcare professional. It's important not to use more than directed or apply more frequently than prescribed.

    Can I use Lidex Cream/Lyderm on my face?

    It's crucial to follow your healthcare professional's advice. While it can be used on the face, it should be done with caution due to the delicate nature of facial skin. Prolonged use or using on large areas of the face might lead to side effects.

    Are there any side effects?

    Possible side effects include burning, itching, irritation, dryness, or redness at the application site. More serious side effects, like skin thinning, stretch marks, or skin infections, are less common. If you experience any unusual or severe reactions, contact your doctor immediately.

    How long should I use Lidex Cream/Lyderm?

    Use it for the duration prescribed by your doctor. Do not use it for longer than recommended, as prolonged use can increase the risk of side effects.

    What should I do if I miss a dose?

    If you miss a dose, apply it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.

    Can I use cosmetics or other skincare products with Lidex Cream/Lyderm?

    Yes, but it's a good idea to wait until the medication has dried before applying any other products. If in doubt, check with your doctor or pharmacist.

    Should I cover the treated area with a bandage?

    Unless directed by a healthcare provider, do not cover the treated area with a bandage or other occlusive dressing, as this can increase the absorption of the medication and the risk of side effects.

    How should I store Lidex Cream/Lyderm?

    Store at room temperature away from moisture and heat. Do not freeze. Keep out of reach of children.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 2176

  • Product Reviews


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