What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Lopressor (Metoprolol Tartrate)
Generic Equivalent - Lopressor (Metoprolol Tartrate)
Prescription Required
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Product Details
Description
Lopressor is prescribed to treat various heart conditions, including high blood pressure, heart attack, abnormal heart rhythm, and coronary artery disease.
Lopressor works by reducing the workload of the heart and blood vessels.
Fact Table
Formula
C15H25NO3
License
US FDA
Bioavailability
50%
Legal status
Rx-only
Chemical Name
Metoprolol
Elimination half-life
3–7 hours
Dosage (Strength)
25mg, 37.5mg, 50mg, 75mg, 100mg
Pregnancy
Consult Doctor
Brands
Lopressor, Metolar XR
Protein binding
12%
PubChem CID
4171
MedlinePlus
a682864
ChEBI
6904
ATC code
C07AB02
DrugBank
DB00264
KEGG
D02358
Routes of administration
By mouth
Directions
Take Lopressor exactly as prescribed by your doctor.
The usual dosage is 25-400 mg by mouth once daily.
Ingredients
The active ingredient in Lopressor is metoprolol tartrate.
Interactions
Common drug-drug interactions with Lopressor include:
- Acetylcholinesterase Inhibitors
- Ajmaline
- Alfuzosin
- Alpha1-Blockers
- Alpha2-Agonists
- Amifostine
- Amiodarone
- Amphetamines
- Antidiabetic Agents
- Antipsychotic Agents
- Artemether and Lumefantrine
- Barbiturates
- Benperidol
- Beta2-Agonists
- Bradycardia-Causing Agents
- Brigatinib
- Brimonidine
- Bromperidol
- Bupivacaine
- Cannabis
- Ceritinib
- Cholinergic Agonists
- CYP2D6 Inhibitors
- Dexmethylphenidate
- Diazoxide
- Dipyridamole
- Disopyramide
- DOBUTamine
- Dronedarone
- DULoxetine
- EPHEDrine
- EPINEPHrine
- Ergot Derivatives
- Etofylline
- Fexinidazole
- Fingolimod
- Flunarizine
- Grass Pollen Allergen Extract
- Herbal Products with Blood Pressure Increasing Effects
- Herbal Products with Blood Pressure Lowering Effects
- Hydroxychloroquine
- Hypotension-Associated Agents
- Ivabradine
- Lacosamide
- Lercanidipine
- Levodopa-Containing Products
- Lidocaine
- Lormetazepam
- Mavacamten
- Mepivacaine
- Methacholine
- Methoxyflurane
- Methylphenidate
- Midodrine
- Mirabegron
- Molsidomine
- Naftopidil
- Nicergoline
- Nicorandil
- NIFEdipine
- Nitroprusside
- Nonsteroidal Anti-Inflammatory Agents
- Obinutuzumab
- Ozanimod
- Peginterferon Alfa-2b
- PENTobarbital
- Pentoxifylline
- Pholcodine
- Phosphodiesterase 5 Inhibitors
- Ponesimod
- Prostacyclin Analogues
- Quinagolide
- Reserpine
- RifAMPin
- Rivastigmine
- Siponimod
- Succinylcholine
- Sulfonylureas
- Tasimelteon
- Terlipressin
- Theophylline Derivatives
- Tofacitinib
- White Birch Allergen Extract
Cautions
Do not abruptly stop taking this medication.
Tell your doctor if you have a history of kidney disease, liver disease, or diabetes.
Ask your healthcare team for a full list of side effects.
Side Effects
Adverse reactions may include:
- Abdominal Pain
- Accidental Injury
- Alopecia
- Anxiety
- Arterial Insufficiency
- Arthralgia
- Arthritis
- Arthropathy
- Bradycardia
- Bronchospasm
- Bullous Pemphigoid
- Cerebrovascular Accident
- Chest Pain
- Claudication
- Cold Extremity
- Confusion
- Constipation
- Decreased HDL Cholesterol
- Decreased Libido
- Depression
- Diaphoresis
- Diarrhea
- Dizziness
- Drowsiness
- Dyspnea
- Erectile Dysfunction
- Erythroderma
- Exacerbation of Psoriasis
- Fatigue
- First-Degree Atrioventricular Block
- Flatulence
- Gangrene of Skin and/or Subcutaneous Tissues
- Hallucination
- Headache
- Heart Failure
- Heartburn
- Hepatic Insufficiency
- Hepatitis
- Hypotension
- Impotence
- Increased Serum Alkaline Phosphatase
- Increased Serum Transaminases
- Increased Serum Triglycerides
- Insomnia
- Jaundice
- Lichenoid Dermatitis
- Musculoskeletal Pain
- Nausea
- Nervousness
- Nightmares
- Palpitations
- Paresthesia
- Pemphigoid-Like Lesion
- Peripheral Edema
- Peyronie Disease
- Pruritus
- Retroperitoneal Fibrosis
- Rhinitis
- Skin Rash
- Sleep Disturbance
- Stomach Pain
- Syncope
- Temporary Amnesia
- Tinnitus
- Unstable Diabetes
- Vertigo
- Visual Disturbance
- Vomiting
- Weight Gain
- Wheezing
- Xerostomia
References
Lopressor [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corp.; 2008.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1612
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