Description
Lopressor is prescribed to treat various heart conditions, including high blood pressure, heart attack, abnormal heart rhythm, and coronary artery disease.
Lopressor works by reducing the workload of the heart and blood vessels.
Fact Table |
Formula |
C15H25NO3 |
License |
US FDA |
Bioavailability |
50% |
Legal status |
Rx-only |
Chemical Name |
Metoprolol |
Elimination half-life |
3–7 hours |
Dosage (Strength) |
25mg, 37.5mg, 50mg, 75mg, 100mg |
Pregnancy |
Consult Doctor |
Brands |
Lopressor, Metolar XR |
Protein binding |
12% |
PubChem CID |
4171 |
MedlinePlus |
a682864 |
ChEBI |
6904 |
ATC code |
C07AB02 |
DrugBank |
DB00264 |
KEGG |
D02358 |
Routes of administration |
By mouth |
Directions
Take Lopressor exactly as prescribed by your doctor.
The usual dosage is 25-400 mg by mouth once daily.
Ingredients
The active ingredient in Lopressor is metoprolol tartrate.
Interactions
Common drug-drug interactions with Lopressor include:
- Acetylcholinesterase Inhibitors
- Ajmaline
- Alfuzosin
- Alpha1-Blockers
- Alpha2-Agonists
- Amifostine
- Amiodarone
- Amphetamines
- Antidiabetic Agents
- Antipsychotic Agents
- Artemether and Lumefantrine
- Barbiturates
- Benperidol
- Beta2-Agonists
- Bradycardia-Causing Agents
- Brigatinib
- Brimonidine
- Bromperidol
- Bupivacaine
- Cannabis
- Ceritinib
- Cholinergic Agonists
- CYP2D6 Inhibitors
- Dexmethylphenidate
- Diazoxide
- Dipyridamole
- Disopyramide
- DOBUTamine
- Dronedarone
- DULoxetine
- EPHEDrine
- EPINEPHrine
- Ergot Derivatives
- Etofylline
- Fexinidazole
- Fingolimod
- Flunarizine
- Grass Pollen Allergen Extract
- Herbal Products with Blood Pressure Increasing Effects
- Herbal Products with Blood Pressure Lowering Effects
- Hydroxychloroquine
- Hypotension-Associated Agents
- Ivabradine
- Lacosamide
- Lercanidipine
- Levodopa-Containing Products
- Lidocaine
- Lormetazepam
- Mavacamten
- Mepivacaine
- Methacholine
- Methoxyflurane
- Methylphenidate
- Midodrine
- Mirabegron
- Molsidomine
- Naftopidil
- Nicergoline
- Nicorandil
- NIFEdipine
- Nitroprusside
- Nonsteroidal Anti-Inflammatory Agents
- Obinutuzumab
- Ozanimod
- Peginterferon Alfa-2b
- PENTobarbital
- Pentoxifylline
- Pholcodine
- Phosphodiesterase 5 Inhibitors
- Ponesimod
- Prostacyclin Analogues
- Quinagolide
- Reserpine
- RifAMPin
- Rivastigmine
- Siponimod
- Succinylcholine
- Sulfonylureas
- Tasimelteon
- Terlipressin
- Theophylline Derivatives
- Tofacitinib
- White Birch Allergen Extract
Cautions
Do not abruptly stop taking this medication.
Tell your doctor if you have a history of kidney disease, liver disease, or diabetes.
Ask your healthcare team for a full list of side effects.
Side Effects
Adverse reactions may include:
- Abdominal Pain
- Accidental Injury
- Alopecia
- Anxiety
- Arterial Insufficiency
- Arthralgia
- Arthritis
- Arthropathy
- Bradycardia
- Bronchospasm
- Bullous Pemphigoid
- Cerebrovascular Accident
- Chest Pain
- Claudication
- Cold Extremity
- Confusion
- Constipation
- Decreased HDL Cholesterol
- Decreased Libido
- Depression
- Diaphoresis
- Diarrhea
- Dizziness
- Drowsiness
- Dyspnea
- Erectile Dysfunction
- Erythroderma
- Exacerbation of Psoriasis
- Fatigue
- First-Degree Atrioventricular Block
- Flatulence
- Gangrene of Skin and/or Subcutaneous Tissues
- Hallucination
- Headache
- Heart Failure
- Heartburn
- Hepatic Insufficiency
- Hepatitis
- Hypotension
- Impotence
- Increased Serum Alkaline Phosphatase
- Increased Serum Transaminases
- Increased Serum Triglycerides
- Insomnia
- Jaundice
- Lichenoid Dermatitis
- Musculoskeletal Pain
- Nausea
- Nervousness
- Nightmares
- Palpitations
- Paresthesia
- Pemphigoid-Like Lesion
- Peripheral Edema
- Peyronie Disease
- Pruritus
- Retroperitoneal Fibrosis
- Rhinitis
- Skin Rash
- Sleep Disturbance
- Stomach Pain
- Syncope
- Temporary Amnesia
- Tinnitus
- Unstable Diabetes
- Vertigo
- Visual Disturbance
- Vomiting
- Weight Gain
- Wheezing
- Xerostomia
References
Lopressor [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corp.; 2008.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 1612