A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Mavik (Trandolapril)
Also Known as Gopten
Brand
Mavik (Trandolapril)
Prescription Required
Strength
Qty
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MAVIK (trandolapril) is a prescription medication used to lower high blood pressure. Since high blood pressure is a component of several diseases, it can be used to treat the following:
Heart failure with reduced ejection fraction (HFrEF)
Hypertension
Left ventricular dysfunction
Post- heart attack heart failure
MAVIK is a type of medication called an ACE inhibitor. It prevents the conversion of angiotensin I to angiotensin II, which decreases blood pressure. MAVIK is converted to its active form in the liver.
Fact Table
Formula
C24H34N2O5
License
US FDA
Bioavailability
10%
Legal status
Rx-only
Chemical Name
Trandolapril
Elimination half-life
6 hours
Dosage (Strength)
1mg, 2mg, 4mg
Pregnancy
Not Recommended
Brands
Mavik
Protein binding
80%
PubChem CID
5484727
MedlinePlus
a697010
ChEBI
9649
ATC code
C09AA10
DrugBank
DB00519
KEGG
D00383
Routes of administration
By mouth
Directions
Take MAVIK exactly as prescribed by your healthcare provider. It should be taken once daily on an empty stomach.
The initial dose of MAVIK is 1 mg by mouth once daily. The dose should be increased to a maximum dose of 4 mg by mouth once daily.
MAVIK is available in 1 mg, 2 mg, and 4 mg tablets.
Ingredients
The active ingredient in MAVIK is trandolapril.
Interactions
Common drug-drug interactions with MAVIK may include:
Aliskiren
Amifostine
Angiotensin II receptors blockers
Bromperidol
Grass pollen allergen extract
Iron dextran complex
Lanthanum
Lithium
Obinutuzumab
Sacubitril
Sodium phosphates
Cautions
Do not take MAVIK if you are pregnant or breastfeeding. MAVIK is toxic to the developing fetus and should be stopped as soon as pregnancy is detected.
Tell your doctor if you develop a dry cough while taking MAVIK.
Your doctor should monitor for increased blood potassium while you are taking MAVIK.
Tell your doctor if you have a history of kidney or liver dysfunction.
Tell your doctor if you have a history of cardiovascular disease before starting MAVIK.
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 2428
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