What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Persantine (Dipyridamole)
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Product Details
Description
After surgery, your doctor may prescribe Persantine to prevent blood clots. Blood clots occur during the healing process, which can break off and cause permanent damage. Persantine helps to prevent the formation of these clots.
The active ingredient in Persantine is dipyridamole. Its mechanism of action involves widening the blood vessels, thereby improving blood flow and enhancing oxygen delivery to the heart.
Fact Table
Formula
C24H40N8O4
License
US FDA
Bioavailability
37–66%
Legal status
Rx-Only
Chemical Name
Dipyridamole
Elimination half-life
a phase: 40 min, ß phase: 10 hours
Dosage (Strength)
25mg, 75mg, 100mg
Pregnancy
Consult Doctor
Brands
Persantine
Protein binding
~99%
PubChem CID
3108
MedlinePlus
a682830
ChEBI
4653
ATC code
B01AC07
DrugBank
DB00975
KEGG
D00302
Routes of administration
By mouth
Directions
The usual Persantine dosage is 75 mg four times a day.
Ingredients
The active ingredient in Persantine is dipyridamole.
Interactions
Common drug-drug interactions include:
- Abrocitinib
- Acalabrutinib
- Acetylcholinesterase Inhibitors
- Adenosine
- Agents with Antiplatelet Properties
- Anagrelide
- Anticoagulants
- Apixaban
- Bemiparin
- Beta-Blockers
- Caplacizumab
- Cephalothin
- Cladribine
- Collagenase (Systemic)
- Dabigatran Etexilate
- Dasatinib
- Deoxycholic Acid
- Edoxaban
- Enoxaparin
- Heparin
- Herbal Products with Anticoagulant/Antiplatelet Effects
- Ibritumomab Tiuxetan
- Ibrutinib
- Icosapent Ethyl
- Inotersen
- Lecanemab
- Limaprost
- Obinutuzumab
- Omega-3 Fatty Acids
- Pentosan Polysulfate Sodium
- Pentoxifylline
- Pirtobrutinib
- Prostacyclin Analogues
- Regadenoson
- Riociguat
- Rivaroxaban
- Salicylates
- Selumetinib
- Thrombolytic Agents
- Tipranavir
- Urokinase
- Vitamin E
- Zanubrutinib
Cautions
Use Persantine with caution if you have a history of bleeding disorders, low blood pressure, or liver or kidney problems. It is important to inform your doctor about any other medications you are currently taking, as they may interact with Persantine.
Side Effects
Common side effects may include:
- Abdominal distress
- Abdominal pain
- Alopecia
- Angina pectoris
- Arthritis
- Arthralgia
- Ataxia
- Back pain
- Bronchospasm
- Cardiac arrhythmia
- Cardiomyopathy
- Cholelithiasis
- Cough
- Depersonalization
- Diaphoresis
- Diarrhea
- Dizziness
- Dysgeusia
- Dyspepsia
- Dysphagia
- Dyspnea
- ECG abnormality
- Edema
- Eructation
- Fatigue
- Flatulence
- Flushing
- Hepatic insufficiency
- Hepatitis
- Hypersensitivity reaction
- Hypertension
- Hypertonia
- Hyperventilation
- Hypotension
- Injection site reaction
- Laryngeal edema
- Leg cramps (intermittent claudication)
- Malaise
- Mastalgia
- Muscle rigidity
- Myalgia
- Myocardial infarction
- Nausea
- Orthostatic hypotension
- Otalgia
- Pain
- Palpitations
- Paresthesia
- Perineal pain
- Pharyngitis
- Pleuritic chest pain
- Pruritus
- Renal pain
- Rhinitis
- Skin rash
- Syncope
- Tachycardia
- Tenesmus
- Tinnitus
- Tremor
- Urticaria
- Vertigo
- Visual disturbance
- Vomiting
- Weakness
- Xerostomia
References
- Persantine [package insert]. Ridgefield, CT : Boehringer Ingelheim Pharmaceuticals, Inc.; 2019.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1719
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