What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Pletal (Cilostazol)

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Brand

Pletal (Cilostazol)

Prescription Required

Strength
Qty
50mg
100mg

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Generic Equivalent - Pletal (Cilostazol)

Prescription Required

Strength
Qty
50mg
100mg

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

  • Product Details

    Description

    Pletal (cilostazol) is classified as a phosphodiesterase III inhibitor (PDE III inhibitor) used to reduce the symptoms of intermittent claudication, as demonstrated by an increased walking distance.

    Pletal is available in 50 mg and 100 mg tablets.


    Fact Table

    Formula

    C20H27N5O2

    License

    US DailyMed

    Bioavailability

    90%

    Legal status

    Rx-Only

    Chemical Name

    Cilostazol

    Elimination half-life

    11–13 hours

    Dosage (Strength)

    50mg, 100mg

    Pregnancy

    contraindicated

    Brands

    Pletal

    Protein binding

    95–98%

    PubChem CID

    2754

    MedlinePlus

    a601038

    ChEBI

    31401

    ATC code

    B01AC23

    DrugBank

    DB01166

    KEGG

    D01896

    Routes of administration

    By mouth (tablets)

    Directions

    The recommended dosage is 100 mg by mouth twice daily. Take 30 minutes before or two hours after breakfast and dinner.

    The dosage may be 50 mg by mouth twice daily when taken with certain medications such as ketoconazole, itraconazole, erythromycin, diltiazem, ticlopidine, fluconazole, and omeprazole. 

    Ingredients

    Each tablet contains the active ingredient, Cilostazol

    Contraindications

    Do not take Pletal if you have heart failure.

    Do not take Pletal if you are allergic to cilostazol or any of the other ingredients in Pletal. Be sure to discuss your allergies with your doctor. 

    Cautions

    WARNING: CONTRAINDICATED IN HEART FAILURE PATIENTS

    See full prescribing information for complete boxed warning.

    PLETAL is contraindicated in patients with heart failure of any severity. Cilostazol and several of its metabolites are inhibitors of phosphodiesterase III. Several drugs with the pharmacologic effect have caused decreased survival compared to placebo patients with class III-IV heart failure. 

    Tell your doctor if you have heart problems. Pletal may increase your heart rate or cause palpitations or low blood pressure.

    Left ventricular outflow tract obstruction has been reported in some patients who received Pletal. Once you are prescribed and buy Pletal, then you should be monitored for a new murmur or heart symptoms after starting Pletal.

    Pletal may cause low blood counts.

    Pletal may cause hemostatic disorders or bleeding and should not be used in these patients.

    Tell your doctor about any medications you are taking, including prescription and over-the-counter medications.

    Your doctor should know if you are pregnant or plan to become pregnant and if you are breastfeeding or plan to breastfeed.

    Side Effects

    Pletal may cause side effects, including:

    • Abdominal pain
    • Abnormal stools
    • Diarrhea
    • Dizziness
    • Headache
    • Increased heart rate
    • Indigestion
    • Infection
    • Palpitation
    • Pharyngitis
    • Swelling of your legs or hands


    Tell your doctor right away if you experience any side effects while taking Pletal.

    Reference:

    Pletal Prescribing Information. Rockville, MD: Otsuka America Pharmaceutical, Inc.; 2015.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 2595

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