What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Pred Forte 1% Eye Drops (Prednisolone acetate)
Generic Equivalent - Pred Forte 1% Eye Drops (Prednisolone acetate)
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Product Details
Description
Pred Forte (prednisolone acetate ophthalmic suspension, USP) 1% is a sterile anti-inflammatory eye drop. Pred Forte is used to treat steroid-responsive inflammation of the eye caused by certain eye conditions.
Fact Table
Formula
C21H28O5
License
US FDA, US DailyMed, EU EMA
Bioavailability
approximately 70%
Legal status
Rx-Only
Chemical Name
Prednisolone
Elimination half-life
2–3.5 hours
Dosage (Strength)
1%
Pregnancy
Not Recommended
Brands
Pred Forte
Protein binding
65-91%
PubChem CID
5755
MedlinePlus
a615042
ChEBI
8378
ATC code
A07EA01
DrugBank
DB00860
KEGG
D00472
Routes of administration
By mouth
Directions
Once you have been prescribed and buy Pred Forte, shake the bottle well. Place one to two drops into the affected eye(s) two to four times daily.
Ingredients
The active ingredient in each mL of Pred Forte is prednisolone acetate 1%. Prednisolone acetate is a glucocorticoid.
Contraindications
Do not use Pred Forte if you have an acute purulent eye infection, a viral eye disease, a mycobacteria eye infection, or a fungal eye disease.
Talk to your doctor about any allergies you may have. Do not use Pred Forte if you are allergic to any of the ingredients in Pred Forte or if you are allergic to other corticosteroids.
Cautions
Once you are prescribed and buy Pred Forte, and before you start using Pred Forte, tell your doctor about all medications you are taking. This includes prescriptions, over-the-counter, herbal supplements, and vitamins. Pred Forte may interact with some medications.
Sodium bisulfite is found in Pred Forte and can cause a potentially severe allergic reaction in people who are sensitive to sulfite.
If Pred Forte is used for a long time, posterior subcapsular cataracts may form and increase intraocular pressure. This may lead to glaucoma with optic nerve damage and vision problems. Long-term use may also weaken the immune system, increasing the risk for secondary eye infections.
If you will be using Pred Forte eye drops for 10 days or longer, get your intraocular pressure monitored regularly. If you have glaucoma, you should be careful when using steroids and get your intraocular pressure frequently checked.
Prolonged use of corticosteroid eye drops can cause corneal and scleral thinning. If you have a thin cornea or scleral tissue, the use of corticosteroid eye drops may cause perforation.
Corticosteroid eye drops may mask or worsen acute purulent eye infections.
Healing can take longer or blebs may form if you use steroids after cataract surgery.
Tell your doctor if you have ever had herpes simplex. Using steroid eye drops may lengthen the course of and worsen viral eye infections such as herpes simplex.
Tell your doctor if you still have eye pain or inflammation after 48 hours.
Be careful not to touch the bottle tip to the eyelids or any other surface as this can cause an eye infection or injury. Do not share the bottle.
Pred Forte contains benzalkonium chloride that can be absorbed by soft contact lenses. Be sure to remove your contact lenses before placing the drops into your eye(s). You may put your contacts in 15 minutes after you place the drops.
Tell your doctor if you are pregnant or planning to become pregnant. Pred Forte should only be used during pregnancy if the benefits outweigh the risks.
Tell your doctor if you are breastfeeding or planning to breastfeed. Pred Forte may pose a risk for adverse effects in nursing infants. The decision to stop breastfeeding or to stop using Pred Forte should be made, considering the importance of Pred Forte to the mother.
Side Effects
Pred Forte, like all medications, can have side effects. If you experience any adverse effects while using Pred Forte, be sure to tell your doctor. Pred Forte side effects may include:
- Allergic reactions
- Altered taste
- Eye pain
- Feeling like something is in your eye
- Headache
- Itching
- Rash
- Burning and/or stinging after instilling the drops
- Hives
- Blurry vision
Reference:
PRED FORTEPrescribing Information. Madison, NJ: Allergan, 2020.
Frequently Asked Questions about Pred Forte
What is Pred Forte used for?
Pred Forte is used to treat eye inflammation, reducing irritation, burning, redness, and swelling caused by allergies, chemical or thermal burns, radiation, or foreign objects in the eye.
What should I tell my doctor before using Pred Forte?
Inform your doctor if you have allergies to prednisolone or any other part of Pred Forte, bacterial eye infections, fungal, TB, or viral infections of the eye, or if you are breastfeeding.
Are there any precautions for using Pred Forte?
Consult your doctor if you have a history of eye ulcers, glaucoma, cataract surgery, or other eye infections. Avoid using Pred Forte if you are allergic to its ingredients, have eye infections, or recently had herpes simplex.
Can children and the elderly use Pred Forte?
Pred Forte has not been tested in children under 18 and is not recommended for them. It has, however, been deemed safe for use in the elderly.
Are there any drug interactions with Pred Forte?
Certain medicines, especially some for HIV (ritonavir, cobicistat), may increase the effects of Pred Forte. Inform your doctor about all medications you're taking.
How should Pred Forte be used?
Use Pred Forte as prescribed by your doctor. The typical dosage is 1 or 2 drops in the affected eye(s) 2 to 4 times a day, possibly more frequently during the first two days of treatment.
What should I do if I miss a dose or use too much Pred Forte?
If you miss a dose, use it as soon as you remember. If it's nearly time for your next dose, skip the missed dose. If you use more Pred Forte than you should, wash your eye(s) with clean water but avoid taking a double dose to make up for a missed one.
What are the side effects of Pred Forte?
Side effects can include eye ulcers, severe eye pain, allergic reactions, increased eye pressure, cataracts, irritation, blurred vision, and changes in taste. If these occur, consult your doctor immediately.
How should Pred Forte be stored?
Store Pred Forte at room temperature, away from heat and light, and keep it out of reach of children. Discard the bottle 28 days after opening, even if there is remaining solution. Do not use after the expiry date.
What precautions should be taken regarding driving and contact lens use?
Pred Forte may cause temporary blurred vision, so avoid driving or using machinery until this clears. Remove contact lenses before using Pred Forte and wait 15 minutes before reinserting them, as the medication contains benzalkonium chloride, which can be absorbed by soft lenses and cause irritation.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 2234
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