What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Sinemet (Carbidopa/Levodopa)
Also Known as Sinemet Plus
Prescription Required
-
Related Products & Conditions
-
Product Details
Description
Sinemet Uses
Chemical Name: CARBIDOPA (KAR-bi-doe-pa) and LEVODOPA (LEE-voe-doe-pa)Sinemet medication is made up of a combination of two substances that are known as levodopa and carbidopa. Sinemet uses include treating symptoms of Parkinson's disease that may include tremors, shaking, stiffness, or movement issues. It is caused due to reduced levels of dopamine (a neurotransmitter in the brain that affects emotions and movement) in the brain. Levodopa belongs to the type of drugs known as central nervous system agents. This substance works by converting itself into dopamine and restoring levels of dopamine reaching the brain.
Carbidopa works by preventing the breakdown of levodopa while moving through the bloodstream to reach the brain. It also helps reduce side effects of levodopa itself such as nausea.
The good news is that you can purchase this medicine online from Canada Pharmacy and get genuine products delivered to your house. You will have assurance of quality.
Fact Table
Formula
C10H14NO4 (Levodopa), C10H14N2O4 (Carbidopa)
License
US FDA
Bioavailability
Levodopa: ~40–70%
Legal status
Rx-only
Chemical Name
Levodopa: (S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid Carbidopa: (2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid
Elimination half-life
Levodopa: ~1.5 hours; Carbidopa: ~2–3 hours
Dosage (Strength)
10/100 mg, 25/100 mg, 25/250 mg tablets
Pregnancy
Use only if clearly needed; consult physician
Brands
Sinemet, Parcopa (ODT), Rytary (ER), Duopa (gel)
Protein binding
Levodopa: <10%; Carbidopa: ~36%
PubChem CID
Levodopa: 6047; Carbidopa: 34359
MedlinePlus
a684001
ChEBI
Levodopa: 15765; Carbidopa: 3429
ATC code
N04BA02
DrugBank
Levodopa: DB01235; Carbidopa: DB00190
KEGG
Levodopa: D08103; Carbidopa: D03472
Routes of administration
Oral
Directions
This medicine needs to be taken through the mouth. You may choose to take it with or without a meal. The usual dosage is three to four times every day or as prescribed by your doctor according to your medical condition, age, and body weight. Do not alter dosages or skip doses.
Ingredients
Sinemet is supplied in three strengths:
- Sinemet 25-100 that contains 25 mg of carbidopa and 100 mg of levodopa.
- Sinemet 10-100, 10 mg and 100 mg carbidopa levodopa respectively.
- Sinemet 25-250 which contains 25 mg of carbidopa and 250 mg of levodopa.
Sinemet Parkinson's tablet also contains other inactive ingredients such as:
- Hydroxypropyl cellulose
- Pregelatinized starch
- Crospovidone
- Microcrystalline cellulose
- Magnesium stearate.
SINEMET 10-100 and 25-250 Tablets also contain FD&C Blue #2/Indigo Carmine AL. SINEMET 25-100 Tablets also contain D&C Yellow #10 Lake.
Cautions
- May cause dizziness, do not engage in activities such as driving and operating machinery until fully alert.
- Limit use of alcohol when using this drug.
- Pregnant women should use this medication with a doctor's prescription.
- Breastfeeding females should consult a doctor too as levodopa passes through breast milk.
Side Effects
Common side effects of Sinemet medication are as follows:
- Lethargy
- Dry mouth
- Headache
- Insomnia
- Upset stomach such as constipation, diarrhea, etc.
- Vomiting
- Dizziness
- Bad dreams
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1802
-
Product Reviews