What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Xenical (Orlistat)
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Product Details
Description
Xenical is a prescription medication used for weight reduction in obese patients on a calorie-restricted diet. Xenical may also be used to reduce the risk of weight regain after weight loss.
Xenical works by preventing the absorption of nutrients into the bloodstream.
Directions
Xenical is usually taken up to three times daily with meals. The usual dosage is 120 mg.
Xenical can be taken with or up to one hour after meals.
Speak with your healthcare provider to ensure you are consuming a nutritionally balanced diet while taking Xenical.
Ingredients
Orlistat is the active ingredient in Xenical.
Interactions
Xenical inhibits the absorption of many drugs. Therefore, you should tell your doctor or pharmacist about all medications you are taking, including:
- Amiodarone
- Atazanavir
- Carbamazepine
- Cyclosporine
- Darunavir
- Fosamprenavir
- Gabapentin
- Indinavir
- Lamotrigine
- Levetiracetam
- Levothyroxine
- Lopinavir
- Multivitamins
- Nelfinavir
- Phenytoin
- Propafenone
- Ritonavir
- Sincalide
- Triheptanoin
Fact Table
Formula
C29H53NO5
License
EU EMA, USA FDA
Bioavailability
Negligible
Legal status
Varies
Chemical Name
Orlistat
Elimination half-life
1 to 2 hours
Dosage (Strength)
120mg
Pregnancy
Consult a doctor
Brands
Xenical, Alli
Protein binding
99%
PubChem CID
3034010
MedlinePlus
a601244
ChEBI
94686
ATC code
A08AB01
DrugBank
DB01083
KEGG
D04028
Routes of administration
Oral
Cautions
Most patients should take a multivitamin containing fat-soluble vitamins while using Xenical.
Tell your doctor if you have a history of gout or liver problems.
Speak with your healthcare provider or pharmacist before using Xenical.
Side Effects
Some of the common side effects from Xenical may include:
- Abdominal distress
- Abdominal pain
- Anxiety
- Bowel urgency
- Fatigue
- Fecal incontinence
- Flatulence with discharge
- Frequent bowel movements
- Gingival disease
- Headache
- Infectious diarrhea
- Influenza
- Low blood sugar
- Menstrual disease
- Nausea
- Oily evacuation
- Oily rectal leakage
- Otitis
- Pedal edema
- Rectal pain
- Sleep disorders
- Steatorrhea
- Urinary tract infection
- Vaginitis
- Xeroderma
References
Xenical [package insert]. San Francisco, CA: Genentech; 2012.
Frequently Asked Questions about Xenical
What is Xenical?
Xenical is a prescription medication used to help overweight or obese individuals lose weight. It works by blocking the absorption of fat in the body.
How does Xenical work?
Xenical works by inhibiting the activity of lipase enzymes in the digestive system. This reduces the absorption of dietary fat, leading to weight loss over time.
Who is a suitable candidate for Xenical treatment?
Xenical is typically recommended for adults who are obese or overweight with a BMI (Body Mass Index) of 30 or higher or for those with a BMI of 27 or higher and other obesity-related health conditions.
Is Xenical a substitute for a healthy diet and exercise?
No, Xenical is not a substitute for a healthy diet and regular physical activity. It should be used in conjunction with a reduced-calorie diet and a proper exercise program.
How is Xenical taken?
Xenical is usually taken three times a day with meals containing fat. It should be taken as directed by a healthcare provider.
What are the common side effects of Xenical?
Common side effects may include oily spotting, gas, stomach cramps, and increased bowel movements. These side effects are often related to the medication's mechanism of action.
How long does it take to see results with Xenical?
The rate of weight loss with Xenical can vary among individuals. Some people may start to see results within a few weeks, while others may take longer. Consistency with treatment is important.
Can Xenical be used for long-term weight management?
Xenical is generally recommended for short-term use, and its long-term safety and effectiveness are still being studied. It's essential to discuss your treatment plan with a healthcare provider.
Are there any dietary restrictions while taking Xenical?
While taking Xenical, it's advisable to reduce the intake of high-fat foods to minimize side effects. A healthcare provider or dietitian can provide specific dietary guidance.
Is Xenical safe for everyone?
Xenical may not be suitable for everyone, and its use should be discussed with a healthcare provider. Individuals with certain medical conditions or allergies to the active ingredient (Orlistat) should not take Xenical.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1909
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