Description
Xenical is a prescription medication used for weight reduction in obese patients on a calorie-restricted diet. Xenical may also be used to reduce the risk of weight regain after weight loss.
Xenical works by preventing the absorption of nutrients into the bloodstream.
Directions
Xenical is usually taken up to three times daily with meals. The usual dosage is 120 mg.
Xenical can be taken with or up to one hour after meals.
Speak with your healthcare provider to ensure you are consuming a nutritionally balanced diet while taking Xenical.
Ingredients
Orlistat is the active ingredient in Xenical.
Interactions
Xenical inhibits the absorption of many drugs. Therefore, you should tell your doctor or pharmacist about all medications you are taking, including:
- Amiodarone
- Atazanavir
- Carbamazepine
- Cyclosporine
- Darunavir
- Fosamprenavir
- Gabapentin
- Indinavir
- Lamotrigine
- Levetiracetam
- Levothyroxine
- Lopinavir
- Multivitamins
- Nelfinavir
- Phenytoin
- Propafenone
- Ritonavir
- Sincalide
- Triheptanoin
Fact Table |
Formula |
C29H53NO5 |
License |
EU EMA, USA FDA |
Bioavailability |
Negligible |
Legal status |
Varies |
Chemical Name |
Orlistat |
Elimination half-life |
1 to 2 hours |
Dosage (Strength) |
120mg |
Pregnancy |
Consult a doctor |
Brands |
Xenical, Alli |
Protein binding |
99% |
PubChem CID |
3034010 |
MedlinePlus |
a601244 |
ChEBI |
94686 |
ATC code |
A08AB01 |
DrugBank |
DB01083 |
KEGG |
D04028 |
Routes of administration |
Oral |
Cautions
Most patients should take a multivitamin containing fat-soluble vitamins while using Xenical.
Tell your doctor if you have a history of gout or liver problems.
Speak with your healthcare provider or pharmacist before using Xenical.
Side Effects
Some of the common side effects from Xenical may include:
- Abdominal distress
- Abdominal pain
- Anxiety
- Bowel urgency
- Fatigue
- Fecal incontinence
- Flatulence with discharge
- Frequent bowel movements
- Gingival disease
- Headache
- Infectious diarrhea
- Influenza
- Low blood sugar
- Menstrual disease
- Nausea
- Oily evacuation
- Oily rectal leakage
- Otitis
- Pedal edema
- Rectal pain
- Sleep disorders
- Steatorrhea
- Urinary tract infection
- Vaginitis
- Xeroderma
References
Xenical [package insert]. San Francisco, CA: Genentech; 2012.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 1909