What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Zanaflex (Tizanidine HCl)


Zanaflex (Tizanidine HCl)

Prescription Required


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Generic Equivalent - Zanaflex (Tizanidine HCl)

Prescription Required


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  • Product Details


    Zanaflex is a prescription muscle relaxant that can be used for the management of muscle spasms. It works by activating alpha-2-adrenergic receptors, which cause the relaxation of muscle cells.

    Fact Table




    US FDA



    Legal status

    RX Only

    Chemical Name


    Elimination half-life

    2.5 hours

    Dosage (Strength)

    2mg (150 tablets), 4mg (150 tablets)


    Consult a doctor



    Protein binding


    PubChem CID






    ATC code






    Routes of administration

    By mouth (tablets)


    Take Zanaflex exactly as prescribed by your doctor. The recommended starting dosage is 2 mg every 6-8 hours. Do not take more than three doses in 24 hours unless directed by your doctor.

    The dosage may be increased to 2-4 mg every 6-8 hours. Do not increase more frequently than every 1-4 days.

    The maximum total daily dose is 36 mg.


    The active ingredient in Zanaflex is tizanidine.

    Zanaflex capsules are available in Zanaflex 2 mg, Zanaflex 4 mg, and Zanaflex 6 mg.

    Zanaflex tablets are available in Zanaflex 4 mg.


    Tell your doctor and pharmacist about all medications you are taking before starting Zanaflex because it has the potential for many drug-drug interactions.

    • Abametapir
    • Artemisinin
    • Atazanavir
    • Azelastine
    • Bromperidol
    • Ciprofloxacin
    • Ciprofloxacin
    • Enoxacin
    • Ethinyl Estradiol
    • Fluvoxamine
    • Mexiletine
    • Tacrine
    • Thiabendazole
    • Zileuton


    If Zanaflex was taken for a long period and is going to be stopped, it should be tapered slowly to reduce the risk of high blood pressure, fast heart rate, and muscle spasms.

    Tell your doctor if you have a history of low blood pressure before starting this medication.

    Zanaflex can cause sedation. Do not operate a vehicle before you know how it affects you.

    Tell your doctor if you have a history of kidney or liver problems.

    Side Effects

    Some common Zanaflex side effects may include:

    • Abametapir
    • Amifostine
    • Artemisinin
    • Atazanavir
    • Azelastine
    • Beta-blockers
    • Bromperidol
    • Buprenorphine
    • Ceritinib
    • Ciprofloxacin
    • Ciprofloxacin
    • Enoxacin
    • Ethinyl Estradiol
    • Flunitrazepam
    • Fluvoxamine
    • Mexiletine
    • Mirtazapine
    • Obinutuzumab
    • Opioids
    • Orphenadrine
    • Suvorexant
    • Tacrine
    • Thalidomide
    • Thiabendazole
    • Tricyclic Antidepressants
    • Zileuton

    Frequently Asked Questions about Zanaflex

    What is Zanaflex?

    Zanaflex is a prescription medication that is used to treat muscle spasms and spasticity. It is also known by its generic name, tizanidine.

    How does Zanaflex work?

    Zanaflex works by blocking nerve signals in the spinal cord that cause muscles to tighten. This helps to reduce muscle spasms and spasticity.

    What conditions are typically treated with Zanaflex?

    Zanaflex is often prescribed for conditions such as multiple sclerosis (MS), spinal cord injuries, and other neurological disorders that result in muscle spasms or spasticity.

    Is Zanaflex a painkiller or muscle relaxant?

    Zanaflex is classified as a muscle relaxant. It does not directly relieve pain but can help alleviate pain associated with muscle spasms and spasticity.

    How is Zanaflex taken?

    Zanaflex is usually taken orally, with or without food, as directed by your healthcare provider. The dosage and frequency will depend on your specific condition and response to the medication.

    What are the common side effects of Zanaflex?

    Common side effects of Zanaflex may include drowsiness, dizziness, dry mouth, and weakness. It's essential to follow your healthcare provider's instructions and report any unusual or severe side effects.

    How quickly does Zanaflex take effect?

    Zanaflex typically begins to take effect within 1 to 2 hours after taking a dose. It may take a few days of regular use to experience its full benefits.

    Is it safe to drive or operate heavy machinery while taking Zanaflex?

    Zanaflex can cause drowsiness and dizziness. It is recommended to avoid activities that require mental alertness, such as driving or operating machinery, until you know how Zanaflex affects you.

    Can I stop taking Zanaflex suddenly?

    It is important not to stop taking Zanaflex abruptly without consulting your healthcare provider. They may need to gradually reduce your dosage to avoid withdrawal symptoms.

    Are there any dietary restrictions when taking Zanaflex?

    There are no specific dietary restrictions associated with Zanaflex. However, it's important to maintain a healthy diet and lifestyle to support your overall well-being.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1911

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