Description
Zanaflex is a prescription muscle relaxant that can be used for the management of muscle spasms. It works by activating alpha-2-adrenergic receptors, which cause the relaxation of muscle cells.
Directions
Take Zanaflex exactly as prescribed by your doctor. The recommended starting dosage is 2 mg every 6-8 hours. Do not take more than three doses in 24 hours unless directed by your doctor.
The dosage may be increased to 2-4 mg every 6-8 hours. Do not increase more frequently than every 1-4 days.
The maximum total daily dose is 36 mg.
Ingredients
The active ingredient in Zanaflex is tizanidine.
Zanaflex capsules are available in Zanaflex 2 mg, Zanaflex 4 mg, and Zanaflex 6 mg.
Zanaflex tablets are available in Zanaflex 4 mg.
Interactions
Tell your doctor and pharmacist about all medications you are taking before starting Zanaflex because it has the potential for many drug-drug interactions.
- Abametapir
- Artemisinin
- Atazanavir
- Azelastine
- Bromperidol
- Ciprofloxacin
- Ciprofloxacin
- Enoxacin
- Ethinyl Estradiol
- Fluvoxamine
- Mexiletine
- Tacrine
- Thiabendazole
- Zileuton
Fact Table |
Formula |
C9H9Cl2N5S |
License |
US FDA |
Bioavailability |
40% |
Legal status |
RX Only |
Chemical Name |
Tizanidine |
Elimination half-life |
2.5 hours |
Dosage (Strength) |
2mg (150 tablets), 4mg (150 tablets) |
Pregnancy |
Consult a doctor |
Brands |
Zanaflex |
Protein binding |
30% |
PubChem CID |
114869 |
MedlinePlus |
a601121 |
ChEBI |
9609 |
ATC code |
R06AE07 |
DrugBank |
DB00697 |
KEGG |
- |
Routes of administration |
By mouth (tablets) |
Cautions
If Zanaflex was taken for a long period and is going to be stopped, it should be tapered slowly to reduce the risk of high blood pressure, fast heart rate, and muscle spasms.
Tell your doctor if you have a history of low blood pressure before starting this medication.
Zanaflex can cause sedation. Do not operate a vehicle before you know how it affects you.
Tell your doctor if you have a history of kidney or liver problems.
Side Effects
Some common Zanaflex side effects may include:
- Abametapir
- Amifostine
- Artemisinin
- Atazanavir
- Azelastine
- Beta-blockers
- Bromperidol
- Buprenorphine
- Ceritinib
- Ciprofloxacin
- Ciprofloxacin
- Enoxacin
- Ethinyl Estradiol
- Flunitrazepam
- Fluvoxamine
- Mexiletine
- Mirtazapine
- Obinutuzumab
- Opioids
- Orphenadrine
- Suvorexant
- Tacrine
- Thalidomide
- Thiabendazole
- Tricyclic Antidepressants
- Zileuton
About Dr. Alex Covey (Page Author)
Alex Covey studies chemistry and microbiology as an undergraduate before moving on to pharmacy school and completing his Pharm D. His professional focus is on early phase clinical research but also has background experience in inpatient hospital, community pharmacy, and specialty compounding. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 1911