What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Zanaflex (Tizanidine HCl)
Prescription Required
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Product Details
Description
Zanaflex is a prescription muscle relaxant that can be used for the management of muscle spasms. It works by activating alpha-2-adrenergic receptors, which cause the relaxation of muscle cells.
Directions
Take Zanaflex exactly as prescribed by your doctor. The recommended starting dosage is 2 mg every 6-8 hours. Do not take more than three doses in 24 hours unless directed by your doctor.
The dosage may be increased to 2-4 mg every 6-8 hours. Do not increase more frequently than every 1-4 days.
The maximum total daily dose is 36 mg.
Ingredients
The active ingredient in Zanaflex is tizanidine.
Zanaflex capsules are available in Zanaflex 2 mg, Zanaflex 4 mg, and Zanaflex 6 mg.
Zanaflex tablets are available in Zanaflex 4 mg.
Interactions
Tell your doctor and pharmacist about all medications you are taking before starting Zanaflex because it has the potential for many drug-drug interactions.
- Abametapir
- Artemisinin
- Atazanavir
- Azelastine
- Bromperidol
- Ciprofloxacin
- Ciprofloxacin
- Enoxacin
- Ethinyl Estradiol
- Fluvoxamine
- Mexiletine
- Tacrine
- Thiabendazole
- Zileuton
Fact Table
Formula
C9H9Cl2N5S
License
US FDA
Bioavailability
40%
Legal status
RX Only
Chemical Name
Tizanidine
Elimination half-life
2.5 hours
Dosage (Strength)
2mg (150 tablets), 4mg (150 tablets)
Pregnancy
Consult a doctor
Brands
Zanaflex
Protein binding
30%
PubChem CID
114869
MedlinePlus
a601121
ChEBI
9609
ATC code
R06AE07
DrugBank
DB00697
KEGG
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Routes of administration
By mouth (tablets)
Cautions
If Zanaflex was taken for a long period and is going to be stopped, it should be tapered slowly to reduce the risk of high blood pressure, fast heart rate, and muscle spasms.
Tell your doctor if you have a history of low blood pressure before starting this medication.
Zanaflex can cause sedation. Do not operate a vehicle before you know how it affects you.
Tell your doctor if you have a history of kidney or liver problems.
Side Effects
Some common Zanaflex side effects may include:
- Abametapir
- Amifostine
- Artemisinin
- Atazanavir
- Azelastine
- Beta-blockers
- Bromperidol
- Buprenorphine
- Ceritinib
- Ciprofloxacin
- Ciprofloxacin
- Enoxacin
- Ethinyl Estradiol
- Flunitrazepam
- Fluvoxamine
- Mexiletine
- Mirtazapine
- Obinutuzumab
- Opioids
- Orphenadrine
- Suvorexant
- Tacrine
- Thalidomide
- Thiabendazole
- Tricyclic Antidepressants
- Zileuton
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1911
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